DPABH-05283

antibody from Creative Diagnostics

Targeting: CDC45 CDC45L, CDC45L2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DPABH-05283

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-05283, RRID:AB_2509249

Product name

Rabbit Anti-Human CDC45 Polyclonal Antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at 4°C. Avoid freeze / thaw cycles.