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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN359531 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LRRN6A.
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody at 2 - 8°C up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models.
TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.
Inoue H, Lin L, Lee X, Shao Z, Mendes S, Snodgrass-Belt P, Sweigard H, Engber T, Pepinsky B, Yang L, Beal MF, Mi S, Isacson O
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 4;104(36):14430-5
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 4;104(36):14430-5
TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.
Satoh J, Tabunoki H, Yamamura T, Arima K, Konno H
Neuropathology and applied neurobiology 2007 Feb;33(1):99-107
Neuropathology and applied neurobiology 2007 Feb;33(1):99-107
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of LINGO1 (arrow) using rabbit polyclonal LINGO1 Antibody (N-term) (AP14015PU-N). 293 cell lysates (2 μg/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 Antibody (N-term) (AP14015PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
