AMM03762G

antibody from Leading Biology

Targeting: MAP2K5 HsT17454, MAPKK5, MEK5, PRKMK5

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

AMM03762G

Provider

Leading Biology

Product name

MAP2K5 Antibody (monoclonal) (M11)

Antibody type

Monoclonal

Description

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3E11

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.