Ab099911

antibody from Aladdin Scientific Corporation

Targeting: DVL1

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab099911

Provider

Aladdin Scientific Corporation

Product name

Dishevelled/Dvl1 Antibody

Antibody type

Polyclonal

Description

Rabbit anti Human Dishevelled/Dvl1 Antibody, Polyclonal, could be used for WB, IHC and so on.Application:WB: 0.01-2µg/mLIHC: 5-20µg/mLProtein FunctionParticipates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 150-285


Vial size

100μl,10μl,1ml,20μl,50μl

Concentration

Lot by Lot

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.