Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60767 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PTPN21 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human PTPN21.
- Description
- The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PTPN21 (protein tyrosine phosphatase, non-receptor type 21), also known as PTPD1 or PTPRL10, is a 1,174 amino acid member of the PTP family and localizes to both the cytoplasm and the cytoskeleton. Containing one FERM domain and one tyrosine-protein phosphatase domain, PTPN21 functions to catalyze the water-dependent conversion of a protein tyrosine phosphate into a protein tyrosine and a free phosphate and, via this catalytic activity, may be involved in liver regeneration and spermatogenesis. The gene encoding PTPN21 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of PTPN21 pAb at 1:500 dilutionLane1:A549 whole cell lysateLane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate