ABIN499271

antibody from antibodies-online

Targeting: AMBRA1 DCAF3, FLJ20294, KIAA1736, WDR94

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN499271

Provider

antibodies-online

Product name

anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Ambra1 antibody was raised against a 15 amino acid peptide from near the carboxyterminus of human Ambra1. (ABIN499270)

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.

References

Submitted references

Ambra1 regulates autophagy and development of the nervous system.

Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, Nardacci R, Corazzari M, Fuoco C, Ucar A, Schwartz P, Gruss P, Piacentini M, Chowdhury K, Cecconi F
Nature 2007 Jun 28;447(7148):1121-5

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Autophagy as a cell death and tumor suppressor mechanism.

Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906

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Induction of autophagy and inhibition of tumorigenesis by beclin 1.

Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B
Nature 1999 Dec 9;402(6762):672-6

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Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.

Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO
Carcinogenesis 1993 Dec;14(12):2501-5

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of Ambra1 in 3T3 cell lysate with AP30047PU-N Ambra1 antibody at 1 ?g/ml.

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunohistochemistry of Ambra1 in human brain with AP30047PU-N Ambra1 antibody at 5 ?g/ml.