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antibody from antibodies-online
Targeting: CACNA1A
APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN1742171 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) (AA 865-881), (Intracellular) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide corresponding to amino acid residues 865-881 of rat CaV2.1. Intracellular loop between domains II and III.
- Description
- Affinity purified on immobilized antigen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antigen sequence
(C)PSSPERAPGREGPYGRE- Epitope
- AA 865-881,Intracellular
- Vial size
- 50 μL
- Storage
- The reconstituted solution can be stored at 4°C for up to 2 weeks. For longer periods, it is recommended to add glycerol at a ratio of 1:1 and to keep the antibody solution at -20°C.
- Handling
- Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Submitted references Presynaptic Cav2.1 and Cav2.2 differentially influence release dynamics at hippocampal excitatory synapses.
Familial hemiplegic migraine mutations increase Ca(2+) influx through single human CaV2.1 channels and decrease maximal CaV2.1 current density in neurons.
Splicing of alpha 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels.
Scheuber A, Miles R, Poncer JC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Nov 17;24(46):10402-9
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Nov 17;24(46):10402-9
Familial hemiplegic migraine mutations increase Ca(2+) influx through single human CaV2.1 channels and decrease maximal CaV2.1 current density in neurons.
Tottene A, Fellin T, Pagnutti S, Luvisetto S, Striessnig J, Fletcher C, Pietrobon D
Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 1;99(20):13284-9
Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 1;99(20):13284-9
Splicing of alpha 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels.
Bourinet E, Soong TW, Sutton K, Slaymaker S, Mathews E, Monteil A, Zamponi GW, Nargeot J, Snutch TP
Nature neuroscience 1999 May;2(5):407-15
Nature neuroscience 1999 May;2(5):407-15
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
