13818-1-AP

antibody from Proteintech Group

Targeting: SEPTIN7 CDC10, CDC3, SEPT7, SEPT7A

Provider product page for 13818-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [16]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

Submit

Product number: 13818-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13818-1-AP, RRID:AB_2254298
Product name: Septin 7 antibody
Antibody type: Polyclonal
Description: KD/KO validated Septin 7 antibody (Cat. #13818-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

SEPTIN7 protein structure - 13818-1-AP shown in red.

Submitted references AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis.

Wu S, Li L, Wu X, Wong CKC, Sun F, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21925

HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization.

Wu S, Frank I, Derby N, Martinelli E, Cheng CY
Endocrinology 2021 Nov 1;162(11)

Sperm-borne miR-202 targets SEPT7 and regulates first cleavage of bovine embryos via cytoskeletal remodeling.

Wang M, Du Y, Gao S, Wang Z, Qu P, Gao Y, Wang J, Liu Z, Zhang J, Zhang Y, Qing S, Wang Y
Development (Cambridge, England) 2021 Mar 5;148(5)

Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties.

Soroor F, Kim MS, Palander O, Balachandran Y, Collins RF, Benlekbir S, Rubinstein JL, Trimble WS
Molecular biology of the cell 2021 Feb 1;32(3):289-300

Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.

Kandi R, Senger K, Grigoryan A, Soller K, Sakk V, Schuster T, Eiwen K, Menon MB, Gaestel M, Zheng Y, Florian MC, Geiger H
EMBO reports 2021 Dec 6;22(12):e52931

Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone.

Wiegering A, Dildrop R, Vesque C, Khanna H, Schneider-Maunoury S, Gerhardt C
Molecular biology of the cell 2021 Apr 15;32(8):675-689

KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.

Wu S, Lv L, Li L, Wang L, Mao B, Li J, Shen X, Ge R, Wong CKC, Sun F, Cheng CY
Endocrinology 2021 Apr 1;162(4)

SEPT7 regulates Ca²⁺ entry through Orai channels in human neural progenitor cells and neurons.

Deb BK, Chakraborty P, Gopurappilly R, Hasan G
Cell calcium 2020 Sep;90:102252

The septin cytoskeleton regulates natural killer cell lytic granule release.

Phatarpekar PV, Overlee BL, Leehan A, Wilton KM, Ham H, Billadeau DD
The Journal of cell biology 2020 Nov 2;219(11)

Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.

Danson CM, Pearson N, Heesom KJ, Cullen PJ
Journal of cell science 2018 Sep 10;131(17)

Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts.

Farrugia AJ, Calvo F
Small GTPases 2017 Jan 2;8(1):49-57

Still and rotating myosin clusters determine cytokinetic ring constriction.

Wollrab V, Thiagarajan R, Wald A, Kruse K, Riveline D
Nature communications 2016 Jul 1;7:11860

Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit.

Gera N, Yang A, Holtzman TS, Lee SX, Wong ET, Swanson KD
PloS one 2015;10(5):e0125269

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.

Calvo F, Ranftl R, Hooper S, Farrugia AJ, Moeendarbary E, Bruckbauer A, Batista F, Charras G, Sahai E
Cell reports 2015 Dec 29;13(12):2699-714

Role of endothelial cell septin 7 in the endocytosis of Candida albicans.

Phan QT, Eng DK, Mostowy S, Park H, Cossart P, Filler SG
mBio 2013 Dec 17;4(6):e00542-13

Uncovering principles that control septin-septin interactions.

Kim MS, Froese CD, Xie H, Trimble WS
The Journal of biological chemistry 2012 Aug 31;287(36):30406-13

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HepG2 cells were subjected to SDS PAGE followed by western blot with 13818-1-AP(SEPT7 antibody) at dilution of 1:2000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human lung cancer using 13818-1-AP(SEPT7 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human lung cancer using 13818-1-AP(SEPT7 antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue