Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 13818-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13818-1-AP, RRID:AB_2254298
- Product name
- Septin 7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Septin 7 antibody (Cat. #13818-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function.
The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis.
Salmonella engages CDC42 effector protein 1 for intracellular invasion.
The Septin Cytoskeleton is Required for Plasma Membrane Repair.
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Splenectomy improves erythrocyte functionality in spherocytosis based on septin abundance, but not maturation defects.
Stable expression and multi-site location of Odf2 in mouse oocytes, sperm and early embryos.
SEPTIN 7 INTERACTS WITH NUMB TO PRESERVE SARCOMERE STRUCTURAL ORGANIZATION AND MUSCLE CONTRACTILE FUNCTION.
An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis.
AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis.
HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization.
Sperm-borne miR-202 targets SEPT7 and regulates first cleavage of bovine embryos via cytoskeletal remodeling.
Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties.
Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.
Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone.
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
SEPT7 regulates Ca(2+) entry through Orai channels in human neural progenitor cells and neurons.
The septin cytoskeleton regulates natural killer cell lytic granule release.
Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.
Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts.
Still and rotating myosin clusters determine cytokinetic ring constriction.
Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit.
Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.
Role of endothelial cell septin 7 in the endocytosis of Candida albicans.
Uncovering principles that control septin-septin interactions.
De Gasperi R, Csernoch L, Dienes B, Gonczi M, Chakrabarty JK, Goeta S, Aslan A, Toro CA, Karasik D, Brown LM, Brotto M, Cardozo CP
eLife 2024 May 2;12
eLife 2024 May 2;12
The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis.
Holley CL, Emming S, Monteleone MM, Mellacheruvu M, Kenney KM, Lawrence GMEP, Coombs JR, Burgener SS, Schroder K
Cell chemical biology 2024 May 16;31(5):962-972.e4
Cell chemical biology 2024 May 16;31(5):962-972.e4
Salmonella engages CDC42 effector protein 1 for intracellular invasion.
Bandyopadhyay S, Zhang X, Ascura A, Edelblum KL, Bonder EM, Gao N
Journal of cellular physiology 2024 Jan;239(1):36-50
Journal of cellular physiology 2024 Jan;239(1):36-50
The Septin Cytoskeleton is Required for Plasma Membrane Repair.
Prislusky MI, Lam JG, Contreras VR, Ng M, Chamberlain M, Pathak-Sharma S, Fields M, Zhang X, Amer AO, Seveau S
bioRxiv : the preprint server for biology 2024 Jan 6;
bioRxiv : the preprint server for biology 2024 Jan 6;
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Splenectomy improves erythrocyte functionality in spherocytosis based on septin abundance, but not maturation defects.
Cloos AS, Pollet H, Stommen A, Maja M, Lingurski M, Brichard B, Lambert C, Henriet P, Pierreux C, Pyr Dit Ruys S, Van Der Smissen P, Vikkula M, Gatto L, Martin M, Brouillard P, Vertommen D, Tyteca D
Blood advances 2023 Sep 12;7(17):4705-4720
Blood advances 2023 Sep 12;7(17):4705-4720
Stable expression and multi-site location of Odf2 in mouse oocytes, sperm and early embryos.
Xu X, Jiang X, Song K, Zhang J, Tian Y, Chen Y, Weng J, Liang Y, Ma W
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Oct;250:152126
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Oct;250:152126
SEPTIN 7 INTERACTS WITH NUMB TO PRESERVE SARCOMERE STRUCTURAL ORGANIZATION AND MUSCLE CONTRACTILE FUNCTION.
Gasperi R, Csernoch L, Dienes B, Gonczi M, Chakrabarty JK, Goeta S, Aslan A, Toro CA, Karasik D, Brown LM, Brotto M, Cardozo CP
bioRxiv : the preprint server for biology 2023 Nov 16;
bioRxiv : the preprint server for biology 2023 Nov 16;
An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis.
Panagiotou TC, Chen A, Wilde A
Cell reports 2022 Aug 30;40(9):111274
Cell reports 2022 Aug 30;40(9):111274
AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis.
Wu S, Li L, Wu X, Wong CKC, Sun F, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21925
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21925
HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization.
Wu S, Frank I, Derby N, Martinelli E, Cheng CY
Endocrinology 2021 Nov 1;162(11)
Endocrinology 2021 Nov 1;162(11)
Sperm-borne miR-202 targets SEPT7 and regulates first cleavage of bovine embryos via cytoskeletal remodeling.
Wang M, Du Y, Gao S, Wang Z, Qu P, Gao Y, Wang J, Liu Z, Zhang J, Zhang Y, Qing S, Wang Y
Development (Cambridge, England) 2021 Mar 5;148(5)
Development (Cambridge, England) 2021 Mar 5;148(5)
Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties.
Soroor F, Kim MS, Palander O, Balachandran Y, Collins RF, Benlekbir S, Rubinstein JL, Trimble WS
Molecular biology of the cell 2021 Feb 1;32(3):289-300
Molecular biology of the cell 2021 Feb 1;32(3):289-300
Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.
Kandi R, Senger K, Grigoryan A, Soller K, Sakk V, Schuster T, Eiwen K, Menon MB, Gaestel M, Zheng Y, Florian MC, Geiger H
EMBO reports 2021 Dec 6;22(12):e52931
EMBO reports 2021 Dec 6;22(12):e52931
Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone.
Wiegering A, Dildrop R, Vesque C, Khanna H, Schneider-Maunoury S, Gerhardt C
Molecular biology of the cell 2021 Apr 15;32(8):675-689
Molecular biology of the cell 2021 Apr 15;32(8):675-689
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
Wu S, Lv L, Li L, Wang L, Mao B, Li J, Shen X, Ge R, Wong CKC, Sun F, Cheng CY
Endocrinology 2021 Apr 1;162(4)
Endocrinology 2021 Apr 1;162(4)
SEPT7 regulates Ca(2+) entry through Orai channels in human neural progenitor cells and neurons.
Deb BK, Chakraborty P, Gopurappilly R, Hasan G
Cell calcium 2020 Sep;90:102252
Cell calcium 2020 Sep;90:102252
The septin cytoskeleton regulates natural killer cell lytic granule release.
Phatarpekar PV, Overlee BL, Leehan A, Wilton KM, Ham H, Billadeau DD
The Journal of cell biology 2020 Nov 2;219(11)
The Journal of cell biology 2020 Nov 2;219(11)
Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.
Danson CM, Pearson N, Heesom KJ, Cullen PJ
Journal of cell science 2018 Sep 10;131(17)
Journal of cell science 2018 Sep 10;131(17)
Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts.
Farrugia AJ, Calvo F
Small GTPases 2017 Jan 2;8(1):49-57
Small GTPases 2017 Jan 2;8(1):49-57
Still and rotating myosin clusters determine cytokinetic ring constriction.
Wollrab V, Thiagarajan R, Wald A, Kruse K, Riveline D
Nature communications 2016 Jul 1;7:11860
Nature communications 2016 Jul 1;7:11860
Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit.
Gera N, Yang A, Holtzman TS, Lee SX, Wong ET, Swanson KD
PloS one 2015;10(5):e0125269
PloS one 2015;10(5):e0125269
Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.
Calvo F, Ranftl R, Hooper S, Farrugia AJ, Moeendarbary E, Bruckbauer A, Batista F, Charras G, Sahai E
Cell reports 2015 Dec 29;13(12):2699-714
Cell reports 2015 Dec 29;13(12):2699-714
Role of endothelial cell septin 7 in the endocytosis of Candida albicans.
Phan QT, Eng DK, Mostowy S, Park H, Cossart P, Filler SG
mBio 2013 Dec 17;4(6):e00542-13
mBio 2013 Dec 17;4(6):e00542-13
Uncovering principles that control septin-septin interactions.
Kim MS, Froese CD, Xie H, Trimble WS
The Journal of biological chemistry 2012 Aug 31;287(36):30406-13
The Journal of biological chemistry 2012 Aug 31;287(36):30406-13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 13818-1-AP(SEPT7 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 13818-1-AP(SEPT7 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 13818-1-AP(SEPT7 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue