BS8653

antibody from Bioworld Technology, Inc
Targeting: EIF3C eIF3-p110, EIF3S8
Provider product page for BS8653
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8653 - Provider product page
Provider
Bioworld Technology, Inc
Product name
EIF3C polyclonal antibody
Antibody type
Polyclonal
Antigen
Eukaryotic translation initiation factor 3 subunit C; eIF3c; Eukaryotic translation initiation factor 3 subunit 8; eIF3 p110; EIF3C; EIF3S8
Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EIF3C protein structure - BS8653 shown in red.