Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15548-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15548-1-AP, RRID:AB_2147345
- Product name
- NADK antibody
- Antibody type
- Polyclonal
- Description
- NADK antibody (Cat. #15548-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation.
Human DNA ligase IV is able to use NAD+ as an alternative adenylation donor for DNA ends ligation.
NADP(+) is an endogenous PARP inhibitor in DNA damage response and tumor suppression.
Zhang Y, Xu Y, Lu W, Ghergurovich JM, Guo L, Blair IA, Rabinowitz JD, Yang X
Cell metabolism 2021 Jan 5;33(1):94-109.e8
Cell metabolism 2021 Jan 5;33(1):94-109.e8
Human DNA ligase IV is able to use NAD+ as an alternative adenylation donor for DNA ends ligation.
Chen SH, Yu X
Nucleic acids research 2019 Feb 20;47(3):1321-1334
Nucleic acids research 2019 Feb 20;47(3):1321-1334
NADP(+) is an endogenous PARP inhibitor in DNA damage response and tumor suppression.
Bian C, Zhang C, Luo T, Vyas A, Chen SH, Liu C, Kassab MA, Yang Y, Kong M, Yu X
Nature communications 2019 Feb 11;10(1):693
Nature communications 2019 Feb 11;10(1):693
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- RAW264.7 cells were subjected to SDS PAGE followed by western blot with 15548-1-AP(NADK antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using NADK antibody 15548-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 15548-1-AP(NADK antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 15548-1-AP(NADK antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue