Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3303 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3303, RRID:AB_1578358
- Product name
- PACSIN3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PACSIN3.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family.
All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.
Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.
Sumoy L, Pluvinet R, Andreu N, Estivill X, Escarceller M
Gene 2001 Jan 10;262(1-2):199-205
Gene 2001 Jan 10;262(1-2):199-205
All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.
Modregger J, Ritter B, Witter B, Paulsson M, Plomann M
Journal of cell science 2000 Dec;113 Pt 24:4511-21
Journal of cell science 2000 Dec;113 Pt 24:4511-21
Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.
Howard L, Nelson KK, Maciewicz RA, Blobel CP
The Journal of biological chemistry 1999 Oct 29;274(44):31693-9
The Journal of biological chemistry 1999 Oct 29;274(44):31693-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PACSIN3 polyclonal antibody (Cat # PAB3303) is used in Western blot to detect PACSIN3 in mouse brain tissue lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PACSIN3 polyclonal antibody (Cat # PAB3303) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)