PAB3303

antibody from Abnova Corporation

Targeting: PACSIN3 SDPIII

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB3303

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB3303, RRID:AB_1578358

Product name

PACSIN3 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of PACSIN3.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family.

Sumoy L, Pluvinet R, Andreu N, Estivill X, Escarceller M
Gene 2001 Jan 10;262(1-2):199-205

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All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.

Modregger J, Ritter B, Witter B, Paulsson M, Plomann M
Journal of cell science 2000 Dec;113 Pt 24:4511-21

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Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.

Howard L, Nelson KK, Maciewicz RA, Blobel CP
The Journal of biological chemistry 1999 Oct 29;274(44):31693-9

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

The PACSIN3 polyclonal antibody (Cat # PAB3303) is used in Western blot to detect PACSIN3 in mouse brain tissue lysate.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human cancer tissue reacted with PACSIN3 polyclonal antibody (Cat # PAB3303) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)