FNab06146
antibody from FineTest Biotech
Targeting: PARD3
ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
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- Product number
- FNab06146 - Provider product page
- Provider
- FineTest Biotech
- Product name
- PARD3 antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination(By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.PARD3 has three splice isoforms at 100 kDa, 150 kDa, and 180 kDa. This polyclonal antibody raised against C-terminal 281 amino acids of human PARD3 recognizes these three isoforms.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
Partitioning defective 3 homolog
- Epitope
- IgG
- Isotype
- IgG
- Vial size
- 100¦Ìg
- Concentration
- Immunogen affinity purified
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
- Handling
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
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