ADI-OSA-110-F

antibody from Enzo Life Sciences

Targeting: HMOX1 bK286B10, HO-1

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ADI-OSA-110-F

Provider

Enzo Life Sciences

Product name

HO-1 monoclonal antibody (HO-1-1)

Antibody type

Monoclonal

Antigen

Synthetic peptide

Description

Protein G affinity purified.

Reactivity

Human, Mouse, Rat, Bovine, Canine

Host

Mouse

Isotype

IgG

Antibody clone number

HO-1-1

Vial size

200 μg

Storage

-20°C

References

Submitted references

DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy.

Pettersen K, Monsen VT, Hakvåg Pettersen CH, Overland HB, Pettersen G, Samdal H, Tesfahun AN, Lundemo AG, Bjørkøy G, Schønberg SA
Free radical biology & medicine 2016 Jan;90:158-72

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Nitration of indoxyl sulfate facilitates its cytotoxicity in human renal proximal tubular cells via expression of heme oxygenase-1.

Ishima Y, Narisoko T, Kragh-Hansen U, Kotani S, Nakajima M, Otagiri M, Maruyama T
Biochemical and biophysical research communications 2015 Sep 25;465(3):481-7

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Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation.

Chen HH, Lu PJ, Chen BR, Hsiao M, Ho WY, Tseng CJ
Biochimica et biophysica acta 2015 Oct;1852(10 Pt A):2195-201

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Cytotoxic Effects of Tropodithietic Acid on Mammalian Clonal Cell Lines of Neuronal and Glial Origin.

Wichmann H, Vocke F, Brinkhoff T, Simon M, Richter-Landsberg C
Marine drugs 2015 Nov 27;13(12):7113-23

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Heme oxygenase-1 protects endothelial cells from the toxicity of air pollutant chemicals.

Lawal AO, Zhang M, Dittmar M, Lulla A, Araujo JA
Toxicology and applied pharmacology 2015 May 1;284(3):281-91

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Gastroprotective effect of orexin-A and heme oxygenase system.

Gemici B, Tan R, Birsen I, İzgüt Uysal VN
The Journal of surgical research 2015 Feb;193(2):626-33

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Autophagy Deficiency Diminishes Indomethacin-Induced Intestinal Epithelial Cell Damage through Activation of the ERK/Nrf2/HO-1 Pathway.

Harada S, Nakagawa T, Yokoe S, Edogawa S, Takeuchi T, Inoue T, Higuchi K, Asahi M
The Journal of pharmacology and experimental therapeutics 2015 Dec;355(3):353-61

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Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats.

Jabs A, Oelze M, Mikhed Y, Stamm P, Kröller-Schön S, Welschof P, Jansen T, Hausding M, Kopp M, Steven S, Schulz E, Stasch JP, Münzel T, Daiber A
Vascular pharmacology 2015 Aug;71:181-91

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Impact of aging on heat shock protein expression in the substantia nigra and striatum of the female rat.

Gleixner AM, Pulugulla SH, Pant DB, Posimo JM, Crum TS, Leak RK
Cell and tissue research 2014 Jul;357(1):43-54

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HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction.

Kang HJ, Yi YW, Hong YB, Kim HJ, Jang YJ, Seong YS, Bae I
Scientific reports 2014 Dec 3;4:7201

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Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress.

Fonseca AM, Pereira CF, Porto G, Arosa FA
Free radical biology & medicine 2003 Dec 1;35(11):1404-16

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H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene.

Yoshida T, Maulik N, Ho YS, Alam J, Das DK
Circulation 2001 Mar 27;103(12):1695-701

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Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase.

Hadjur S, Ung K, Wadsworth L, Dimmick J, Rajcan-Separovic E, Scott RW, Buchwald M, Jirik FR
Blood 2001 Aug 15;98(4):1003-11

Immunocytochemistry

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Western blot analysis of HO-1 (Hsp32), mAb (HO-1-1) (Prod. No. ADI-OSA-110): Lane 1: MW marker; Lane 2: HO-1 (rat), (recombinant) (Prod. No. ADI-SPP-730); Lane 3: HO-1 (human), (recombinant) (Prod. No. ADI-SPP-732); Lane 4: HO-2 (human), (recombinant) (Prod. No. ADI-SPP-550); Lane 5: MDBK cell lysate; Lane 6: Dog liver microsome; Lane 7: Mouse liver microsome.

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunohistochemistry analysis of human spleen tissue stained with HO-1, mAb (HO-1-1) at 10µg/ml.