Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 18961-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18961-1-AP, RRID:AB_2064998
- Product name
- BBS7 antibody
- Antibody type
- Polyclonal
- Description
- BBS7 antibody (Cat. #18961-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Photoreceptor cilia, in contrast to primary cilia, grant entry to a partially assembled BBSome.
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Essential role of the chaperonin CCT in rod outer segment biogenesis.
The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome.
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.
Hsu Y, Seo S, Sheffield VC
Human molecular genetics 2021 Mar 25;30(1):87-102
Human molecular genetics 2021 Mar 25;30(1):87-102
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Datta P, Hendrickson B, Brendalen S, Ruffcorn A, Seo S
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.
Hsu Y, Garrison JE, Kim G, Schmitz AR, Searby CC, Zhang Q, Datta P, Nishimura DY, Seo S, Sheffield VC
PLoS genetics 2017 Oct;13(10):e1007057
PLoS genetics 2017 Oct;13(10):e1007057
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Datta P, Allamargot C, Hudson JS, Andersen EK, Bhattarai S, Drack AV, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
Essential role of the chaperonin CCT in rod outer segment biogenesis.
Sinha S, Belcastro M, Datta P, Seo S, Sokolov M
Investigative ophthalmology & visual science 2014 May 22;55(6):3775-85
Investigative ophthalmology & visual science 2014 May 22;55(6):3775-85
The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome.
Chamling X, Seo S, Searby CC, Kim G, Slusarski DC, Sheffield VC
PLoS genetics 2014 Feb;10(2):e1004083
PLoS genetics 2014 Feb;10(2):e1004083
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.
Seo S, Zhang Q, Bugge K, Breslow DK, Searby CC, Nachury MV, Sheffield VC
PLoS genetics 2011 Nov;7(11):e1002358
PLoS genetics 2011 Nov;7(11):e1002358
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 18961-1-AP(BBS7 antibody) at dilution of 1:1500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 18961-1-AP(BBS7 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BBS7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BBS7. This antibody recognizes human,mouse,rat antigen. The BBS7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.