DCABH-7012

antibody from Creative Diagnostics

Targeting: SLC6A4 5-HTT, HTT, OCD1, SERT1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

DCABH-7012

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-7012, RRID:AB_2480391

Product name

Rabbit Anti-Human SLC6A4 monoclonal antibody, clone 27I3M8

Antibody type

Monoclonal

Description

SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

27I3M8

Concentration

0.5 mg/ml

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.