ABIN500533
antibody from antibodies-online
Targeting: PRDM16
KIAA1675, KMT8F, MEL1, MGC166915, PFM13
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN500533 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PR Domain Containing 16 (PRDM16) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- PRDM16 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of Human PRDM16 (AP30689CP-N).
- Description
- Peptide Affinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Upon receipt store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references PRDM16 controls a brown fat/skeletal muscle switch.
Leukemogenesis of the EVI1/MEL1 gene family.
PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.
A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells.
Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM
Nature 2008 Aug 21;454(7207):961-7
Nature 2008 Aug 21;454(7207):961-7
Leukemogenesis of the EVI1/MEL1 gene family.
Morishita K
International journal of hematology 2007 May;85(4):279-86
International journal of hematology 2007 May;85(4):279-86
PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.
Warner DR, Horn KH, Mudd L, Webb CL, Greene RM, Pisano MM
Biochimica et biophysica acta 2007 Jun;1773(6):814-20
Biochimica et biophysica acta 2007 Jun;1773(6):814-20
A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells.
Mochizuki N, Shimizu S, Nagasawa T, Tanaka H, Taniwaki M, Yokota J, Morishita K
Blood 2000 Nov 1;96(9):3209-14
Blood 2000 Nov 1;96(9):3209-14
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of PRDM16 in rat brain tissue lysate with AP30689PU-N PRDM16 antibody at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of PRDM16 in rat brain tissue with AP30689PU-N PRDM16 antibody at 2.5 ?g/ml.