abx016067

antibody from Abbexa

Targeting: POU5F1 MGC22487, OCT3, Oct4, OTF3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx016067

Provider

Abbexa

Product name

POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody

Antibody type

Monoclonal

Description

This gene encodes a transcription factor containing a POU homeodomain.This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency.A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21;q12), has been linked to tumor formation.Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon.Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain.Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.Low levels of expression in adult tissues.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.