WRAP73

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Studies of the related mouse protein suggest that the encoded protein may play a role in the process of ossification. [provided by RefSeq, Mar 2009]

Description

WD repeat containing, antisense to TP73

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (3630767 - 3652761)

Ensembl ID

ENSG00000116213  (ver. 103.38)

Orthologs

Mouse Wrap73: ENSMUSG00000029029

UniProt

Q9P2S5

neXtProt

NX_Q9P2S5

Human splice variants
Mouse splice variants

Protein structure