Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11858-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11858-1-AP, RRID:AB_2234673
- Product name
- Galectin-1 antibody
- Antibody type
- Polyclonal
- Description
- Galectin-1 antibody (Cat. #11858-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq analysis.
Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils.
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
LGALS1 regulates cell adhesion to promote the progression of ovarian cancer.
Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple negative breast cancers to predict clinical treatment.
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
Prognostic Value and Biological Function of Galectins in Malignant Glioma.
Mesenchymal stem cells target microglia via galectin-1 production to rescue aged mice from olfactory dysfunction.
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption.
Galectin‑1 binds GRP78 to promote the proliferation and metastasis of gastric cancer.
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma.
Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.
Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.
Xian W, Asad M, Wu S, Bai Z, Li F, Lu J, Zu G, Brintnell E, Chen H, Mao Y, Zhou G, Liao B, Wu J, Wang E, You L
Frontiers of medicine 2024 Feb;18(1):147-168
Frontiers of medicine 2024 Feb;18(1):147-168
Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils.
Jiang X, Xiao X, Li H, Gong Y, Wang M, Yang H, Zhao L, Jiang Y, Wei Y, Zhao C, Li J, Chen Y, Feng S, Deng H, Ma S, Xu Y, Liu Y, Tsokos GC, Jiang M, Zhang X
Cellular & molecular immunology 2023 Nov;20(11):1339-1351
Cellular & molecular immunology 2023 Nov;20(11):1339-1351
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Hu Z, Zhang Y, Chen J, Luo M, Wang N, Xiao Y, He Q
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
LGALS1 regulates cell adhesion to promote the progression of ovarian cancer.
Li X, Wang H, Jia A, Cao Y, Yang L, Jia Z
Oncology letters 2023 Aug;26(2):326
Oncology letters 2023 Aug;26(2):326
Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple negative breast cancers to predict clinical treatment.
Zheng D, Zhou J, Qian L, Liu X, Chang C, Tang S, Zhang H, Zhou S
Bioactive materials 2023 Apr;22:567-587
Bioactive materials 2023 Apr;22:567-587
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
Gao S, Chao Y, Li N, Li H, Zhao H, Liu X, Chen W, Dong X
Frontiers in medicine 2022;9:805356
Frontiers in medicine 2022;9:805356
Prognostic Value and Biological Function of Galectins in Malignant Glioma.
Zhu H, Liu D, Cheng L, Liu J, Wang G, Li H, Zhang Y, Mi H, Zhang S, Shu K, Yu X
Frontiers in oncology 2022;12:834307
Frontiers in oncology 2022;12:834307
Mesenchymal stem cells target microglia via galectin-1 production to rescue aged mice from olfactory dysfunction.
Seo Y, Ahn JS, Shin YY, Oh SJ, Song MH, Kang MJ, Oh JM, Lee D, Kim YH, Lee BC, Shin TH, Kim HS
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113347
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113347
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Chen Y, Fang Y, Li L, Luo H, Cao T, Tu B
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption.
Li M, Yang D, Yan H, Tang Z, Jiang D, Zhang J, Chi Z, Nie W, Zhen W, Yu W, Chen S, Wang Z, Yu Q, Zhang X, Yang F, Fan S, Lin X, Wang D
Developmental cell 2022 Oct 24;57(20):2365-2380.e8
Developmental cell 2022 Oct 24;57(20):2365-2380.e8
Galectin‑1 binds GRP78 to promote the proliferation and metastasis of gastric cancer.
Zhang Q, Ali M, Wang Y, Sun QN, Zhu XD, Tang D, Wang W, Zhang CY, Zhou HH, Wang DR
International journal of oncology 2022 Nov;61(5)
International journal of oncology 2022 Nov;61(5)
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.
Yang C, Mou Z, Zhang Z, Wu S, Zhou Q, Chen Y, Gong J, Xu C, Ou Y, Chen X, Dai X, Jiang H
Molecular therapy. Nucleic acids 2021 Mar 5;23:872-886
Molecular therapy. Nucleic acids 2021 Mar 5;23:872-886
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma.
Guo XR, Wu MY, Dai LJ, Huang Y, Shan MY, Ma SN, Wang J, Peng H, Ding Y, Zhang QF, Tang JM, Ruan XZ, Li DS
Journal of experimental & clinical cancer research : CR 2019 Sep 6;38(1):394
Journal of experimental & clinical cancer research : CR 2019 Sep 6;38(1):394
Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.
Tummala KS, Brandt M, Teijeiro A, Graña O, Schwabe RF, Perna C, Djouder N
Cell reports 2017 Apr 18;19(3):584-600
Cell reports 2017 Apr 18;19(3):584-600
Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.
Li S, Li X, Wang Y, Yang J, Chen Z, Shan S
BMC microbiology 2014 Feb 7;14:27
BMC microbiology 2014 Feb 7;14:27
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 11858-1-AP(GAL1,LGALS1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Galectin 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Galectin 1. This antibody recognizes human,mouse,rat antigen. The Galectin 1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.