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Learn15554-1-AP
antibody from Proteintech Group
Targeting: PHF5A
bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 15554-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15554-1-AP, RRID:AB_2165365
- Product name
- PHF5A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PHF5A antibody (Cat. #15554-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.
Enterotoxigenic Bacteroidesfragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3p.
PHF5A promotes colorectal cancerprogression by alternative splicing of TEAD2.
RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3.
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
PHD-finger domain protein 5A functions as a novel oncoprotein in lung adenocarcinoma.
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Yu AQ, Wang J, Jiang ST, Yuan LQ, Ma HY, Hu YM, Han XM, Tan LM, Wang ZX
Frontiers in cell and developmental biology 2021;9:710479
Frontiers in cell and developmental biology 2021;9:710479
Enterotoxigenic Bacteroidesfragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3p.
Cao Y, Wang Z, Yan Y, Ji L, He J, Xuan B, Shen C, Ma Y, Jiang S, Ma D, Tong T, Zhang X, Gao Z, Zhu X, Fang JY, Chen H, Hong J
Gastroenterology 2021 Nov;161(5):1552-1566.e12
Gastroenterology 2021 Nov;161(5):1552-1566.e12
PHF5A promotes colorectal cancerprogression by alternative splicing of TEAD2.
Chang Y, Zhao Y, Wang L, Wu M, He C, Huang M, Lei Z, Yang J, Han S, Wang B, Chen Y, Liu C, Yu H, Xue L, Geng J, Chen Y, Dai T, Ren L, Wang Q, Liu X, Chu X, Chen C
Molecular therapy. Nucleic acids 2021 Dec 3;26:1215-1227
Molecular therapy. Nucleic acids 2021 Dec 3;26:1215-1227
RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3.
Karmakar S, Rauth S, Nallasamy P, Perumal N, Nimmakayala RK, Leon F, Gupta R, Barkeer S, Venkata RC, Raman V, Rachagani S, Ponnusamy MP, Batra SK
Gastroenterology 2020 Nov;159(5):1898-1915.e6
Gastroenterology 2020 Nov;159(5):1898-1915.e6
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
Wang Z, Yang X, Liu C, Li X, Zhang B, Wang B, Zhang Y, Song C, Zhang T, Liu M, Liu B, Ren M, Jiang H, Zou J, Liu X, Zhang H, Zhu WG, Yin Y, Zhang Z, Gu W, Luo J
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
PHD-finger domain protein 5A functions as a novel oncoprotein in lung adenocarcinoma.
Yang Y, Zhu J, Zhang T, Liu J, Li Y, Zhu Y, Xu L, Wang R, Su F, Ou Y, Wu Q
Journal of experimental & clinical cancer research : CR 2018 Mar 22;37(1):65
Journal of experimental & clinical cancer research : CR 2018 Mar 22;37(1):65
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Zheng YZ, Xue MZ, Shen HJ, Li XG, Ma D, Gong Y, Liu YR, Qiao F, Xie HY, Lian B, Sun WL, Zhao HY, Yao L, Zuo WJ, Li DQ, Wang P, Hu X, Shao ZM
Cancer research 2018 Jun 15;78(12):3190-3206
Cancer research 2018 Jun 15;78(12):3190-3206
The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Finci LI, Zhang X, Huang X, Zhou Q, Tsai J, Teng T, Agrawal A, Chan B, Irwin S, Karr C, Cook A, Zhu P, Reynolds D, Smith PG, Fekkes P, Buonamici S, Larsen NA
Genes & development 2018 Feb 1;32(3-4):309-320
Genes & development 2018 Feb 1;32(3-4):309-320
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I
Nature cell biology 2016 Nov;18(11):1127-1138
Nature cell biology 2016 Nov;18(11):1127-1138
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PHF5A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PHF5A. This antibody recognizes human,mouse,rat antigen. The PHF5A antibody has been validated for the following applications: ELISA, WB analysis.
