abx016058

antibody from Abbexa

Targeting: SRA1 SRA, STRAA1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx016058

Provider

Abbexa

Product name

Steroid Receptor Rna Activator 1 (SRA) Antibody

Antibody type

Monoclonal

Description

Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs.SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors.Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein.Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis.Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.