Ab094818

antibody from Aladdin Scientific Corporation

Targeting: GP1BA CD42b, GP1B, GPIbalpha

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

Ab094818

Provider

Aladdin Scientific Corporation

Product name

CD42b Mouse mAb

Antibody type

Monoclonal

Description

Mouse monoclonal (6H6H10) to CD42b, could be used for WB, Flow and ELISA.Application:WB: 1/500 - 1/2000; Predicted molecular weight: 72 kDa. Flow: 1/200 - 1/400 ELISA: 1/10000Protein Function:Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

AA: extra 17-183


Isotype

IgG

Antibody clone number

6H6H10

Vial size

100μl,10μl,1ml,50μl

Concentration

1 mg/ml

Storage

Storage: 4℃; -20℃ for long term storage. Avoid repeated freeze/thaw cycles.