CABT-B10207

antibody from Creative Diagnostics

Targeting: ESPL1 ESP1, KIAA0165, SEPA

No application information provided.

Antibody Data

Product number

CABT-B10207

Provider

Creative Diagnostics

Product name

Mouse anti-Human ESPL1 monoclonal antibody, clone YK225E8

Antibody type

Monoclonal

Description

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21