APR05152G

antibody from Leading Biology

Targeting: ESPL1 ESP1, KIAA0165, SEPA

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR05152G

Provider

Leading Biology

Product name

Phospho-SEPARIN(S1126) Antibody

Antibody type

Polyclonal

Description

The metaphase-to-anaphase transition is the final discrete event in duplication and separation of the genetic material of the cell. Its timing is regulated by the activation of the anaphase-promoting complex (APC). In both budding and fission yeast, the degradation of the Pds1 or Cut2 protein, respectively, is required for the onset of sister chromatid separation. Both proteins are APC substrates. Pds1 and Cut2 proteins associate with the yeast separin proteins Esp1 and Cut1, respectively, and prevent the separins from promoting chromatid separation. Pds1 and Cut2 are also called anaphase inhibitors or securins

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.