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- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS61256 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ARHGEF9 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human ARHGEF9.
- Description
- ARHGEF9 (Rho guanine nucleotide exchange factor 9), also known as PEM-2 homolog or Collybistin, is a 516 amino acid cytoplasmic protein. ARHGEF9 acts as a guanine nucleotide exchange factor for Cdc42 and promotes formation of Gephyrin clusters by directly interacting with Gephyrin. ARHGEF9 contains one DH (DBL-homology) domain, one PH domain and one SH3 domain. Defects in the gene encoding ARHGEF9 are a believed to be a cause for startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. This disease is a heterogenous neurological disorder characterized by muscular rigidity, particularly in the neonatal period, and a startle response to auditory or tactile stimuli.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ARHGEF9 pAb at 1:500 dilutionLane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate
