CABT-B12278

antibody from Creative Diagnostics

Targeting: CD300E CD300LE, CLM2, IREM2

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12278

Provider

Creative Diagnostics

Product name

Mouse anti-Human CD300E monoclonal antibody, clone VQ-I3 [FITC]

Antibody type

Monoclonal

Description

The monoclonal antibody UP-H2 reacts with human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells. CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs.

Reactivity

Human

Host

Mouse

Conjugate

Green dye

Isotype

IgG