Ab098863

antibody from Aladdin Scientific Corporation

Targeting: KRT18

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab098863

Provider

Aladdin Scientific Corporation

Product name

Recombinant Cytokeratin 18 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human Cytokeratin 18 Antibody, Primary antibody, could be used for WB, IHC, Flow, IF/ICC, IP and so on.Application:WB: 1/2000 - 1/5000IHC: 1/800 - 1/1600Flow: 1/800 - 1/2000IF/ICC: 1/800 - 1/2000IP: 1/25FunctionInvolved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.Post-translationalPhosphorylation at Ser-34 increases during mitosis. Hyperphosphorylated at Ser-53 in diseased cirrhosis liver. Phosphorylation increases by IL-6. Proteolytically cleaved by caspases during epithelial cell apoptosis. Cleavage occurs at Asp-238 by either caspase-3, caspase-6 or caspase-7. O-glycosylated at multiple sites; glycans consist of single N-acetylglucosamine residues.

Reactivity

Human, Rat

Host

Rabbit

Conjugate

Unconjugated

Antibody clone number

RR693

Vial size

100μl,10μl,1ml,50μl

Concentration

0,5 mg/ml

Storage

Store at -20°C for 2 years. Upon delivery aliquot. Avoid freeze/thaw cycle.