FNab02173

antibody from FineTest Biotech
Targeting: CYP4F3 CYP4F, LTB4H
Provider product page for FNab02173
Western blot
ELISA

Antibody data

Product number
FNab02173 - Provider product page
Provider
FineTest Biotech
Product name
CYP4F3 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Isoform CYP4F3A: Catalyzes the omega-hydroxylation of leukotriene-B(4), a potent chemoattractant for polymorphonuclear leukocytes, it has low activity for arachidonic acid. Isoform CYP4F3B: Shows arachidonic acid omega-hydroxylase activity by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid(20-HETE)(PubMed:11461919, PubMed:16820285). Has a 30-fold higher Km for leukotriene-B(4) compared with CYP4F3A(PubMed:11461919). Also converts eicosapentaenoate(EPA) to 20-hydroxyeicosapentaenoate(20-OH-EPA)(PubMed:16820285). Acts as a polyunsaturated omega-3 fatty acids hydroxylase: mediates conversion of docosahexaenoate(DHA) to 22-hydroxydocosahexaenoate(PubMed:16820285).
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
cytochrome P450, family 4, subfamil
y F, polypeptide 3
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
CYP4F3 protein structure - FNab02173 shown in red.