BS6000

antibody from Bioworld Technology, Inc
Targeting: TNF DIF, TNF-alpha, TNFA, TNFSF2
Provider product page for BS6000
Western blot
Immunohistochemistry

Antibody data

Product number
BS6000 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TNF Ï« polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TNF-Ï«.
Description
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 a band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 a protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TNF protein structure - BS6000 shown in red.