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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- V2900 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- TNF-a Antibody
- Antibody type
- Monoclonal
- Antigen
- Amino acids 115-130 (NGVELRDNQLVVPSEG) from the human protein were used as the immunogen for the TNF-a antibody.
- Description
- PEG precipitated antibody
- Reactivity
- Human, Mouse, Rat, Canine, Feline, Rabbit
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- P/T2
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the TNF-a antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD.
TNF-α promotes invasive growth through the MET signaling pathway.
A histopathologic and immunohistochemical study on liquification of human adipose tissue ex vivo.
Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration.
SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.
Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection.
Angiogenesis and expression of vascular endothelial growth factor, tumour necrosis factor-α and hypoxia inducible factor-1α in canine renal cell carcinoma.
Anaplastic large cell lymphoma with paraneoplastic leukocytosis: a clinicopathological analysis of five cases.
Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer.
Lymphocyte infiltration, expression of interleukin (IL) -1, IL-6 and expression of mutated breast cancer susceptibility gene-1 correlate with malignancy of canine mammary tumours.
IFN-γ promotes THP-1 cell apoptosis during early infection with Mycobacterium bovis by activating different apoptotic signaling.
Resveratrol suppresses colitis and colon cancer associated with colitis.
Lissner D, Schumann M, Batra A, Kredel LI, Kühl AA, Erben U, May C, Schulzke JD, Siegmund B
Inflammatory bowel diseases 2015 Jun;21(6):1297-305
Inflammatory bowel diseases 2015 Jun;21(6):1297-305
TNF-α promotes invasive growth through the MET signaling pathway.
Bigatto V, De Bacco F, Casanova E, Reato G, Lanzetti L, Isella C, Sarotto I, Comoglio PM, Boccaccio C
Molecular oncology 2015 Feb;9(2):377-88
Molecular oncology 2015 Feb;9(2):377-88
A histopathologic and immunohistochemical study on liquification of human adipose tissue ex vivo.
Hübner NF, Horch RE, Polykandriotis E, Rau TT, Dragu A
Aesthetic plastic surgery 2014 Oct;38(5):976-84
Aesthetic plastic surgery 2014 Oct;38(5):976-84
Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration.
Sereti I, Estes JD, Thompson WL, Morcock DR, Fischl MA, Croughs T, Beq S, Lafaye de Micheaux S, Yao MD, Ober A, Wilson EM, Natarajan V, Imamichi H, Boulassel MR, Lederman MM, Routy JP
PLoS pathogens 2014 Jan;10(1):e1003890
PLoS pathogens 2014 Jan;10(1):e1003890
SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.
Mukai T, Ishida S, Ishikawa R, Yoshitaka T, Kittaka M, Gallant R, Lin YL, Rottapel R, Brotto M, Reichenberger EJ, Ueki Y
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Dec;29(12):2618-35
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Dec;29(12):2618-35
Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection.
Tabb B, Morcock DR, Trubey CM, Quiñones OA, Hao XP, Smedley J, Macallister R, Piatak M Jr, Harris LD, Paiardini M, Silvestri G, Brenchley JM, Alvord WG, Lifson JD, Estes JD
The Journal of infectious diseases 2013 Mar 15;207(6):880-92
The Journal of infectious diseases 2013 Mar 15;207(6):880-92
Angiogenesis and expression of vascular endothelial growth factor, tumour necrosis factor-α and hypoxia inducible factor-1α in canine renal cell carcinoma.
Yhee JY, Yu CH, Kim JH, Im KS, Kim NH, Brodersen BW, Doster AR, Sur JH
Journal of comparative pathology 2012 Aug-Oct;147(2-3):129-38
Journal of comparative pathology 2012 Aug-Oct;147(2-3):129-38
Anaplastic large cell lymphoma with paraneoplastic leukocytosis: a clinicopathological analysis of five cases.
Chang IW, Chen HK, Ma MC, Huang WT
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2011 Nov;119(11):794-801
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2011 Nov;119(11):794-801
Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer.
Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P
BMC cancer 2010 Jun 23;10:323
BMC cancer 2010 Jun 23;10:323
Lymphocyte infiltration, expression of interleukin (IL) -1, IL-6 and expression of mutated breast cancer susceptibility gene-1 correlate with malignancy of canine mammary tumours.
Kim JH, Yu CH, Yhee JY, Im KS, Sur JH
Journal of comparative pathology 2010 Feb-Apr;142(2-3):177-86
Journal of comparative pathology 2010 Feb-Apr;142(2-3):177-86
IFN-γ promotes THP-1 cell apoptosis during early infection with Mycobacterium bovis by activating different apoptotic signaling.
Zhang J, Sun B, Huang Y, Kouadir M, Zhou X, Wang Y, Zhao D
FEMS immunology and medical microbiology 2010 Dec;60(3):191-8
FEMS immunology and medical microbiology 2010 Dec;60(3):191-8
Resveratrol suppresses colitis and colon cancer associated with colitis.
Cui X, Jin Y, Hofseth AB, Pena E, Habiger J, Chumanevich A, Poudyal D, Nagarkatti M, Nagarkatti PS, Singh UP, Hofseth LJ
Cancer prevention research (Philadelphia, Pa.) 2010 Apr;3(4):549-59
Cancer prevention research (Philadelphia, Pa.) 2010 Apr;3(4):549-59
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of formalin-fixed, paraffin-embedded human Erdheim Chester disease (also known as polyostotic sclerosing histiocytosis) stained with TNF-a antibody (P/T2).
