APR06634G

antibody from Leading Biology

Targeting: NSMCE2 C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7

Western blot (Recommended by provider)

Antibody Data

Product number

APR06634G

Provider

Leading Biology

Product name

MMS21 Antibody

Antibody type

Polyclonal

Description

MMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.