Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS2038 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS2038, RRID:AB_1662591
- Product name
- LT ÉÇ (V211) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 200-250 of Human LT-ÉÇ.
- Description
- Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-Ï«, also known as TNF?ÉÇ) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. LT-ÉÇ (lymphotaxin-beta or tumor necrosis factor C) is a type II membrane protein with significant homology to TNF, LT-Ï«, and the ligand for the CD40 receptor. LT-Ï« is present on the surface of activated T, B, and LAK cells as a complex with the 33 kda glycoprotein, LT-ÉÇ. LT-ÉÇ, also expressed by active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchors LT-Ï« to the cell surface. A TNF receptor-related protein, the LT-ÉÇ receptor (also known as TNFC receptor), is the human receptor for the LT-Ï«/LT-ÉÇ heterotrimer. There are two LT-ÉÇ isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas. The gene which encodes LT-ÉÇ maps to the major histocompatibility complex region on human chromosome 6p21.3.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of LT-¦Â (V211) pAb at 1:500 dilutionLane1:HepG2 whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate