361502

antibody from BioLegend

Targeting: HLA-DQA1 CELIAC1, HLA-DQA

Immunocytochemistry (Recommended by provider)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

361502

Provider

BioLegend

Proper citation

BioLegend Cat#361502, RRID:AB_2563137

Product name

Purified anti-human HLA-DQ

Antibody type

Monoclonal

Antigen

Human PBL

Description

HLA-DQ is heterodimeric cell surface glycoprotein comprised of a 27 kD α (heavy) chain and a 32 kD β (light) chain. In contrast to other MHC class II molecules, both chains of HLA-DQ are polymorphic and the α chain shows a high degree of polymorphism. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In hematopoietic development, HLA-DR and DP are expressed first, followed by HLA-DQ. Variations in the HLA gene expression are crucial to graft survival.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

Tü169

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

2°C-8°C

Handling

Ambient RT

Flow cytometry

Supportive validation

Submitted by

BioLegend (provider)

Main image

Experimental details

Human peripheral blood lymphocytes were stained with purified HLA-DQ (clone Tü169) (filled histogram) or mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG FITC.

Conjugate

Unconjugated