Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B10243 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human FBXO22 monoclonal antibody, clone 7H0
- Antibody type
- Monoclonal
- Description
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 7H0
- Vial size
- 100 _g
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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