Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP2-20367 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal SIN3B Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Integrative proteomics reveals an increase in non-degradative ubiquitylation in activated CD4(+) T cells.
Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.
Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
Dybas JM, O'Leary CE, Ding H, Spruce LA, Seeholzer SH, Oliver PM
Nature immunology 2019 Jun;20(6):747-755
Nature immunology 2019 Jun;20(6):747-755
Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.
Bainor AJ, Deng FM, Wang Y, Lee P, Cantor DJ, Logan SK, David G
Cancer research 2017 Oct 1;77(19):5339-5348
Cancer research 2017 Oct 1;77(19):5339-5348
Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
Rielland M, Cantor DJ, Graveline R, Hajdu C, Mara L, Diaz Bde D, Miller G, David G
The Journal of clinical investigation 2014 May;124(5):2125-35
The Journal of clinical investigation 2014 May;124(5):2125-35
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: SIN3B Antibody [NBP2-20367] - Sample (30 ug of whole cell lysate) A: HCT116 5% SDS PAGE diluted at 1:500
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunoprecipitation: SIN3B Antibody [NBP2-20367] - Immunoprecipitation of SIN3B protein from HCT-116 whole cell extracts using 5 ug of SIN3B antibody [N1N2], N-term Western blot analysis was performed using SIN3B antibody [N1N2], N-term. EasyBlot anti-Rabbit IgG was used as a secondary reagent.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: SIN3B Antibody [NBP2-20367] - Immunohistochemical analysis of paraffin-embedded MCF7 xenograft, using antibody at 1:100 dilution.