Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10193-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10193-2-AP, RRID:AB_2180018
- Product name
- RCN2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RCN2 antibody (Cat. #10193-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis.
Reticulocalbin 2 as a Potential Biomarker and Therapeutic Target for Atherosclerosis.
A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis.
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
Loss of reticulocalbin 2 lowers blood pressure and restrains ANG II-induced hypertension in vivo.
Reticulocalbin 2 correlates with recurrence and prognosis in colorectal cancer.
Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking.
Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation.
Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.
Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression.
Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation.
Yao H, Zhang S, Xie H, Fan Y, Miao M, Zhu R, Yuan L, Gu M, You Y, You B
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1031-1048
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1031-1048
Reticulocalbin 2 as a Potential Biomarker and Therapeutic Target for Atherosclerosis.
Li J, Taylor AM, Manichaikul A, Angle JF, Shi W
Cells 2022 Mar 25;11(7)
Cells 2022 Mar 25;11(7)
A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis.
Peng H, Hu B, Xie LQ, Su T, Li CJ, Liu Y, Yang M, Xiao Y, Feng X, Zhou R, Guo Q, Zhou HY, Huang Y, Jiang TJ, Luo XH
Cell metabolism 2022 Aug 2;34(8):1168-1182.e6
Cell metabolism 2022 Aug 2;34(8):1168-1182.e6
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
Mei C, Jiang X, Gu Y, Wu X, Ma W, Chen X, Wang G, Yao Y, Liu Y, Zhang Z, Yuan Y
American journal of cancer research 2021;11(5):2238-2251
American journal of cancer research 2021;11(5):2238-2251
Loss of reticulocalbin 2 lowers blood pressure and restrains ANG II-induced hypertension in vivo.
Li J, Cechova S, Wang L, Isakson BE, Le TH, Shi W
American journal of physiology. Renal physiology 2019 Jun 1;316(6):F1141-F1150
American journal of physiology. Renal physiology 2019 Jun 1;316(6):F1141-F1150
Reticulocalbin 2 correlates with recurrence and prognosis in colorectal cancer.
Wang G, Wang Q, Fan Y, He X
American journal of cancer research 2017;7(11):2169-2179
American journal of cancer research 2017;7(11):2169-2179
Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking.
Kaewsapsak P, Shechner DM, Mallard W, Rinn JL, Ting AY
eLife 2017 Dec 14;6
eLife 2017 Dec 14;6
Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation.
Hung V, Lam SS, Udeshi ND, Svinkina T, Guzman G, Mootha VK, Carr SA, Ting AY
eLife 2017 Apr 25;6
eLife 2017 Apr 25;6
Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
Nakakido M, Tamura K, Chung S, Ueda K, Fujii R, Kiyotani K, Nakamura Y
International journal of oncology 2016 Sep;49(3):868-76
International journal of oncology 2016 Sep;49(3):868-76
Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.
Yokoi N, Fukata Y, Kase D, Miyazaki T, Jaegle M, Ohkawa T, Takahashi N, Iwanari H, Mochizuki Y, Hamakubo T, Imoto K, Meijer D, Watanabe M, Fukata M
Nature medicine 2015 Jan;21(1):19-26
Nature medicine 2015 Jan;21(1):19-26
Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression.
Manichaikul A, Wang Q, Shi YL, Zhang Z, Leitinger N, Shi W
American journal of physiology. Heart and circulatory physiology 2011 Sep;301(3):H1056-61
American journal of physiology. Heart and circulatory physiology 2011 Sep;301(3):H1056-61
Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation.
Li L, Sun L, Gao F, Jiang J, Yang Y, Li C, Gu J, Wei Z, Yang A, Lu R, Ma Y, Tang F, Kwon SW, Zhao Y, Li J, Jin Y
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 26;107(4):1402-7
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 26;107(4):1402-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 10193-2-AP(RCN2 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RCN2 antibody 10193-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 10193-2-AP(RCN2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue