CABT-B12184

antibody from Creative Diagnostics

Targeting: IL2RG CD132, CIDX, IMD4, SCIDX1

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12184

Provider

Creative Diagnostics

Product name

Human anti-Human IL2RG recombinant monoclonal antibody, clone SFB424 [PE]

Antibody type

Monoclonal

Description

It recognozes the human CD132 antigen, a 65\u201370 kDa single-pass type I membrane protein also known as common \u03b3 chain, which is shared by the IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 receptors. CD132 is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. The most common form of severe combined immune deficiency in humans, with lack of circulating T cells, a normal or increased number of B lymphocytes, and an X-linked pattern of inheritance (XSCID) has been shown to be due to defects of the CD132 gene. Additional information: It displays negligible binding to Fc receptors.

Reactivity

Human

Host

Human

Conjugate

Yellow dye

Isotype

IgG

Antibody clone number

SFB424

Vial size

for 100 tests

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.