FNab04032

antibody from FineTest Biotech
Targeting: HSD3B7 C(27)-3BETA-HSD, SDR11E3
Provider product page for FNab04032
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab04032 - Provider product page
Provider
FineTest Biotech
Product name
HSD3B7 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis(PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
hydroxy-delta-5-steroid dehydrogena
se, 3 beta-and steroid delta-isomer
ase 7
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
HSD3B7 protein structure - FNab04032 shown in red.