AMAb91130

antibody from Atlas Antibodies

Targeting: CHAT

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AMAb91130

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#AMAb91130, RRID:AB_2665812

Product name

Anti-CHAT

Antibody type

Monoclonal

Description

Monoclonal Antibody against Human CHAT, Clone ID: CL3173, Gene description: choline O-acetyltransferase, Validated applications: IHC, ICC, Uniprot ID: P28329, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

CL3173

Vial size

100 µl

Concentration

1.0 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

4-Phenylbutyric acid mitigates ER stress-induced neurodegeneration in the spinal cords of a GM2 gangliosidosis mouse model

Weaver F, White E, Peek A, Nurse C, Austin R, Igdoura S
Human Molecular Genetics 2025;34(1):32-46

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CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

Ma L, Yang L, Wang X, Zhao L, Bai X, Qi X, Chen Q, Li Y, Zhou Q
Investigative Ophthalmology & Visual Science 2024;65(4):30

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ATH-1105, a small-molecule positive modulator of the neurotrophic HGF system, is neuroprotective, preserves neuromotor function, and extends survival in preclinical models of ALS

Berthiaume A, Reda S, Kleist K, Setti S, Wu W, Johnston J, Taylor R, Stein L, Moebius H, Church K
Frontiers in Neuroscience 2024;18

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Electroacupuncture Promotes Liver Regeneration by Activating DMV Acetylcholinergic Neurons‐Vagus‐Macrophage Axis in 70% Partial Hepatectomy of Mice

Yang L, Zhou Y, Huang Z, Li W, Lin J, Huang W, Sang Y, Wang F, Sun X, Song J, Wu H, Kong X
Advanced Science 2024;11(32)

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Kussick E, Johansen N, Taskin N, Wynalda B, Martinez R, Groce E, Reding M, Liang E, Shulga L, Huang C, Casper T, Clark M, Ho W, Gao Y, van Velthoven C, Sobieski C, Ferrer R, Berg M, Curtis B, English C, Day J, Fortuna M, Donadio N, Newman D, Yao S, Chakka A, Goldy J, Torkelson A, Guzman J, Chakrabarty R, Nguy B, Guilford N, Pham T, Wright V, Ronellenfitch K, Gudsnuk K, Thyagarajan B, Smith K, Dee N, Zeng H, Yao Z, Tasic B, Levi B, Hodge R, Bakken T, Lein E, Ting J, Daigle T
2024

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Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS

Provenzano F, Nyberg S, Giunti D, Torazza C, Parodi B, Bonifacino T, Usai C, Kerlero de Rosbo N, Milanese M, Uccelli A, Shaw P, Ferraiuolo L, Bonanno G
Cells 2022;11(23):3923

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Accumbens Cholinergic Interneurons Mediate Cue-Induced Nicotine Seeking and Associated Glutamatergic Plasticity

Leyrer-Jackson J, Holter M, Overby P, Newbern J, Scofield M, Olive M, Gipson C
eneuro 2021;8(1):ENEURO.0276-20.2020

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human placenta and liver tissues using AMAb91130 antibody. Corresponding CHAT RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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