Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8770 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- METTL7B polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Methyltransferase-like protein 7B; METTL7B; UNQ594/PRO1180
- Description
- METTL7B (methyltransferase-like protein 7B) is a 244 amino acid protein belonging to the methyltransferase superfamily. METTL7B is believed to have methyltransferase activity, wherein METTL7B catalyzes the transfer of a methyl group from one compound to another. The gene that encodes METTL7B maps to chromosome 12 which makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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