Antibody data

Product number
BS60585 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PRSS8 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human PRSS8
Description
Prostasin, a serine protease first identified in prostate tissue, activates epithelial sodium channels in a variety of tissues. Though typically a membrane-anchored protein, free prostasin is also found in physiologic fluids and tissue culture media, indicating a mechanism for secretion from the cells as well. Aprotinin and other protease inhibitors suppress the channel-activating capacity of prostasin, while aldosterone increases prostasin expression and stimulates sodium uptake. In addition, DNA methylation negatively correlates with prostasin expression in cancer cells, while enforced reexpression decreases invasiveness as well as metastatic potential, implying that prostasin activity reflects epithelial cell physiology.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PRSS8 protein structure - BS60585 shown in red.