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- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN1450124 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
Submitted references Distinct physiological and behavioural functions for parental alleles of imprinted Grb10.
Grb10 interacts with Bim L and inhibits apoptosis.
Nuclear factor-kappaB nuclear localization is predictive of biochemical recurrence in patients with positive margin prostate cancer.
Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor.
Grb10 proteins in insulin-like growth factor and insulin receptor signaling (review).
Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function.
Garfield AS, Cowley M, Smith FM, Moorwood K, Stewart-Cox JE, Gilroy K, Baker S, Xia J, Dalley JW, Hurst LD, Wilkinson LS, Isles AR, Ward A
Nature 2011 Jan 27;469(7331):534-8
Nature 2011 Jan 27;469(7331):534-8
Grb10 interacts with Bim L and inhibits apoptosis.
Hu ZQ, Zhang JY, Ji CN, Xie Y, Chen JZ, Mao YM
Molecular biology reports 2010 Oct;37(7):3547-52
Molecular biology reports 2010 Oct;37(7):3547-52
Nuclear factor-kappaB nuclear localization is predictive of biochemical recurrence in patients with positive margin prostate cancer.
Fradet V, Lessard L, Bégin LR, Karakiewicz P, Masson AM, Saad F
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Dec 15;10(24):8460-4
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Dec 15;10(24):8460-4
Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor.
Wick KR, Werner ED, Langlais P, Ramos FJ, Dong LQ, Shoelson SE, Liu F
The Journal of biological chemistry 2003 Mar 7;278(10):8460-7
The Journal of biological chemistry 2003 Mar 7;278(10):8460-7
Grb10 proteins in insulin-like growth factor and insulin receptor signaling (review).
Morrione A
International journal of molecular medicine 2000 Feb;5(2):151-4
International journal of molecular medicine 2000 Feb;5(2):151-4
Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function.
Liu F, Roth RA
Proceedings of the National Academy of Sciences of the United States of America 1995 Oct 24;92(22):10287-91
Proceedings of the National Academy of Sciences of the United States of America 1995 Oct 24;92(22):10287-91
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 antibody Cat.-No AP55623PU-N at (A) 1 and (B) 2 μg/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody Cat.-No AP55623PU-N at 20 μg/ml.
