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- Product number
- 12422-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12422-1-AP, RRID:AB_2162467
- Product name
- Alix antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Alix antibody (Cat. #12422-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A methodological primer of extracellular vesicles isolation and characterization via different techniques.
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107.
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
The Combined Anti-Aging Effect of Hydrolyzed Collagen Oligopeptides and Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells on Human Skin Fibroblasts.
A technique for repeated blood and cerebrospinal fluid sampling from individual rats over time without the need for repeated anesthesia.
Isolation and characterization of small extracellular vesicles from murine primary mammary tumor.
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment.
A novel lung cancer stem cell extracellular vesicles lncRNA ROLLCSC modulate non-stemness cancer cell plasticity through miR-5623-3p and miR-217-5p targeting lipid metabolism.
miRNA profiling of granulosa cell-derived exosomes reveals their role in promoting follicle development.
Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion.
M2 microglia-derived exosome-loaded electroconductive hydrogel for enhancing neurological recovery after spinal cord injury.
Tumour-associated macrophage-derived DOCK7-enriched extracellular vesicles drive tumour metastasis in colorectal cancer via the RAC1/ABCA1 axis.
Palmitoylation of vacuole membrane protein 1 promotes small extracellular vesicle secretion via interaction with ALIX and influences intercellular communication.
Nutrient availability regulates the secretion and function of immune cell-derived extracellular vesicles through metabolic rewiring.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
Insights into the function of ESCRT complex and LBPA in ASFV infection.
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
The iron chelator deferriferrichrysin induces paraptosis via extracellular signal-related kinase activation in cancer cells.
Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.
Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434.
Extracellular Vesicle MicroRNAs From Corneal Stromal Stem Cell Enhance Stemness of Limbal Epithelial Stem Cells by Targeting the Notch Pathway.
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries.
Stress granules plug and stabilize damaged endolysosomal membranes.
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles.
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Canocapavir Is a Novel Capsid Assembly Modulator Inducing a Conformational Change of the Linker Region of HBV Core Protein.
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Autophagy and exosomes coordinately mediate quercetin's protective effects on alcoholic liver disease.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
BMSC-derived extracellular vesicles promoted osteogenesis via Axin2 inhibition by delivering MiR-16-5p.
Phospho-RNA-Seq Highlights Specific Small RNA Profiles in Plasma Extracellular Vesicles.
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Macrophage-derived exosomal miR-195a-5p impairs tubular epithelial cells mitochondria in acute kidney injury mice.
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
NAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a "One-Stone-Two-Birds" manner.
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
Extracellular vesicles released from macrophages modulates interleukin-1β in astrocytic and neuronal cells.
Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells.
Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3/pyroptosis axis: Toward a precision therapy.
Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Exosomes-loaded electroconductive nerve dressing for nerve regeneration and pain relief against diabetic peripheral nerve injury.
Prostate cancer cells synergistically defend against CD8(+) T cells by secreting exosomal PD-L1.
Exosomes Derived from Hypoxia-Cultured Human Adipose Stem Cells Alleviate Articular Chondrocyte Inflammaging and Post-Traumatic Osteoarthritis Progression.
Tumor-derived exosomes orchestrate the microRNA-128-3p/ELF4/CDX2 axis to facilitate the growth and metastasis of gastric cancer via delivery of LINC01091.
Chitosan Nerve Grafts Incorporated with SKP-SC-EVs Induce Peripheral Nerve Regeneration.
Exosomal lipid PI4P regulates small extracellular vesicle secretion by modulating intraluminal vesicle formation.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
LncRNA H19-rich extracellular vesicles derived from gastric cancer stem cells facilitate tumorigenicity and metastasis via mediating intratumor communication network.
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection.
Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes.
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Extracellular vesicle fusion visualized by cryo-electron microscopy.
Vasorin-containing small extracellular vesicles retard intervertebral disc degeneration utilizing an injectable thermoresponsive delivery system.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2.
Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Ischemia-Reperfusion Injury and Promote Survival of Skin Flaps in Rats.
Extracellular vesicles microRNA-592 of melanoma stem cells promotes metastasis through activation of MAPK/ERK signaling pathway by targeting PTPN7 in non-stemness melanoma cells.
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Cancer-derived exosomal circ_0038138 enhances glycolysis, growth, and metastasis of gastric adenocarcinoma via the miR-198/EZH2 axis.
HBV induced the discharge of intrinsic antiviral miRNAs in HBV-replicating hepatocytes via extracellular vesicles to facilitate its replication.
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes.
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
In Vitro and In Vivo Analysis of Extracellular Vesicle-Mediated Metastasis Using a Bright, Red-Shifted Bioluminescent Reporter Protein.
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity.
Serum exosomal proteomics analysis of lung adenocarcinoma to discover new tumor markers.
Recruitment of DNA to tumor-derived microvesicles.
Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Tsc2 mutation induces renal tubular cell nonautonomous disease.
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
In Vivo Visualized Tracking of Tumor-Derived Extracellular Vesicles Using CRISPR-Cas9 System.
A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles.
Tumor-derived extracellular vesicles confer 5-fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery.
Improving the circulation time and renal therapeutic potency of extracellular vesicles using an endogenous ligand binding strategy.
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Effect of plasma-derived extracellular vesicles on angiogenesis and the ensuing proliferative diabetic retinopathy through a miR-30b-dependent mechanism.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles.
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration.
A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization.
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Neddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles.
Tenascin-C expression in the lymph node pre-metastatic niche in muscle-invasive bladder cancer.
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta Delivery.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Mitochondrial Damage and Inflammation by Stabilizing Mitochondrial DNA.
RAB31 marks and controls an ESCRT-independent exosome pathway.
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism.
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Extracellular vesicles derived from lipoaspirate fluid promote fat graft survival.
Surface Nanosieving Polyether Sulfone Particles with Graphene Oxide Encapsulation for the Negative Isolation toward Extracellular Vesicles.
Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration.
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Plasma Exosomal miRNA Expression Profile as Oxaliplatin-Based Chemoresistant Biomarkers in Colorectal Adenocarcinoma.
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Exosomes derived from TSG-6 modified mesenchymal stromal cells attenuate scar formation during wound healing.
Profilin 2 promotes growth, metastasis, and angiogenesis of small cell lung cancer through cancer-derived exosomes.
Isolation of extracellular vesicles from intestinal tissue in a mouse model of intestinal ischemia/reperfusion injury.
DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses.
Tuberous Sclerosis Complex Axis Controls Renal Extracellular Vesicle Production and Protein Content.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
Circulating exosomal small RNAs are promising non-invasive diagnostic biomarkers for gastric cancer.
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis.
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
KLF4-mediated upregulation of CD9 and CD81 suppresses hepatocellular carcinoma development via JNK signaling.
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env(+) tissues.
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Cocktail Strategy Based on NK Cell-Derived Exosomes and Their Biomimetic Nanoparticles for Dual Tumor Therapy.
O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
Exosomes derived from human CD34(+) stem cells transfected with miR-26a prevent glucocorticoid-induced osteonecrosis of the femoral head by promoting angiogenesis and osteogenesis.
Ovarian cancer circulating extracelluar vesicles promote coagulation and have a potential in diagnosis: an iTRAQ based proteomic analysis.
Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8(+) T Cell Responses.
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Cluster of Differentiation 46 Is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28).
Microvesicle-Mediated Delivery of Minicircle DNA Results in Effective Gene-Directed Enzyme Prodrug Cancer Therapy.
Detection of exosomal tyrosine receptor kinase B as a potential biomarker in ovarian cancer.
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α(1)-antitrypsin disposal.
Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response.
CD8α(+)CD11c(+) Extracellular Vesicles in the Lungs Control Immune Homeostasis of the Respiratory Tract via TGF-β1 and IL-10.
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling.
Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity.
Circulating Exosomal miR-17-5p and miR-92a-3p Predict Pathologic Stage and Grade of Colorectal Cancer.
Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.
Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication.
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Regulation of exosomes released from normal ovarian epithelial cells and ovarian cancer cells.
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance.
Characterization of exosomes derived from ovarian cancer cells and normal ovarian epithelial cells by nanoparticle tracking analysis.
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.
Aliakbari F, Stocek NB, Cole-André M, Gomes J, Fanchini G, Pasternak SH, Christiansen G, Morshedi D, Volkening K, Strong MJ
Biology methods & protocols 2024;9(1):bpae009
Biology methods & protocols 2024;9(1):bpae009
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Jin H, Wen X, Sun R, Yu Y, Guo Z, Yang Y, Li L, Sun B
Burns & trauma 2024;12:tkae018
Burns & trauma 2024;12:tkae018
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Yang R, Qu X, Zhi S, Wang J, Fu J, Tan C, Chen H, Wang X
Molecular neurobiology 2024 Sep;61(9):7195-7210
Molecular neurobiology 2024 Sep;61(9):7195-7210
Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107.
Xia J, Wang D, Guo W, Pei Y, Zhang L, Bao L, Li Y, Qu Y, Zhao Y, Hao C, Yao W
International journal of biological macromolecules 2024 May;266(Pt 1):131058
International journal of biological macromolecules 2024 May;266(Pt 1):131058
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Xu L, Li W, Liu D, Cao J, Ge J, Liu X, Wang Y, Teng Y, Liu P, Guo X, He C, Liu M, Tian L
Cancer immunology research 2024 May 2;12(5):614-630
Cancer immunology research 2024 May 2;12(5):614-630
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
Chen Y, Zhang YH, Li J, Shi L, Xie JC, Han X, Chen YT, Xiang M, Li BW, Xing HR, Wang JY
Cancer gene therapy 2024 Mar;31(3):364-375
Cancer gene therapy 2024 Mar;31(3):364-375
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Chen X, Liang Y, Weng Z, Hu C, Peng Y, Sun Y, Gao Q, Huang Z, Tang S, Gong L, Zhang G
PLoS pathogens 2024 Mar;20(3):e1012103
PLoS pathogens 2024 Mar;20(3):e1012103
The Combined Anti-Aging Effect of Hydrolyzed Collagen Oligopeptides and Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells on Human Skin Fibroblasts.
Zhu H, Guo X, Zhang Y, Khan A, Pang Y, Song H, Zhao H, Liu Z, Qiao H, Xie J
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
A technique for repeated blood and cerebrospinal fluid sampling from individual rats over time without the need for repeated anesthesia.
Santandrea E, Aliakbari F, Truscott E, McCaig L, Donison NS, Graham D, Strong MJ, Volkening K
Scientific reports 2024 Mar 2;14(1):5171
Scientific reports 2024 Mar 2;14(1):5171
Isolation and characterization of small extracellular vesicles from murine primary mammary tumor.
Hu S, Zhang X, Yan W
STAR protocols 2024 Mar 15;5(1):102783
STAR protocols 2024 Mar 15;5(1):102783
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Ma W, Wu D, Long C, Liu J, Xu L, Zhou L, Dou Q, Ge Y, Zhou C, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Wang L, Chen J, Song J, Xiang Y, Yang M, Xia L, Yang J, Hou X, Chen L, Wang L
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment.
Dong X, Li C, Deng C, Liu J, Li D, Zhou T, Yang X, Liu Y, Guo Q, Feng Y, Yu Y, Wang Z, Guo W, Zhang S, Cui H, Jiang C, Wang X, Song X, Sun X, Cao L
Oncogene 2024 Jan;43(2):92-105
Oncogene 2024 Jan;43(2):92-105
A novel lung cancer stem cell extracellular vesicles lncRNA ROLLCSC modulate non-stemness cancer cell plasticity through miR-5623-3p and miR-217-5p targeting lipid metabolism.
Zhang YH, Chen Y, Shi L, Han X, Xie JC, Chen Y, Xiang M, Li BW, Li J, Xing HR, Wang JY
International journal of biological macromolecules 2024 Jan;256(Pt 2):128412
International journal of biological macromolecules 2024 Jan;256(Pt 2):128412
miRNA profiling of granulosa cell-derived exosomes reveals their role in promoting follicle development.
Zhou Q, Liu Z, Liao Z, Zhang Y, Qu M, Wu F, Tian J, Zhao H, Peng Q, Zheng W, Huang M, Yang S
Journal of cellular physiology 2024 Jan;239(1):20-35
Journal of cellular physiology 2024 Jan;239(1):20-35
Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion.
Lv K, Lou P, Liu S, Wang Y, Yang J, Zhou P, Zhou X, Lu Y, Wang H, Cheng J, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2024 Jan;20(1):e2303425
Small (Weinheim an der Bergstrasse, Germany) 2024 Jan;20(1):e2303425
M2 microglia-derived exosome-loaded electroconductive hydrogel for enhancing neurological recovery after spinal cord injury.
Guan P, Fan L, Zhu Z, Yang Q, Kang X, Li J, Zhang Z, Liu S, Liu C, Wang X, Xu J, Wang K, Sun Y
Journal of nanobiotechnology 2024 Jan 3;22(1):8
Journal of nanobiotechnology 2024 Jan 3;22(1):8
Tumour-associated macrophage-derived DOCK7-enriched extracellular vesicles drive tumour metastasis in colorectal cancer via the RAC1/ABCA1 axis.
Chen W, Zhou M, Guan B, Xie B, Liu Y, He J, Zhao J, Zhao Q, Yan D
Clinical and translational medicine 2024 Feb;14(2):e1591
Clinical and translational medicine 2024 Feb;14(2):e1591
Palmitoylation of vacuole membrane protein 1 promotes small extracellular vesicle secretion via interaction with ALIX and influences intercellular communication.
Qu M, Liu X, Wang X, Li Z, Zhou L, Li H
Cell communication and signaling : CCS 2024 Feb 26;22(1):150
Cell communication and signaling : CCS 2024 Feb 26;22(1):150
Nutrient availability regulates the secretion and function of immune cell-derived extracellular vesicles through metabolic rewiring.
Wang Y, Lou P, Xie Y, Liu S, Li L, Wang C, Du D, Chen Y, Lu Y, Cheng J, Liu J
Science advances 2024 Feb 16;10(7):eadj1290
Science advances 2024 Feb 16;10(7):eadj1290
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Zhao JL, Zhao L, Zhan QN, Liu M, Zhang T, Chu WW
Current medical science 2024 Apr;44(2):333-345
Current medical science 2024 Apr;44(2):333-345
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Wang S, Li J, Hong S, Wang N, Xu S, Yang B, Zheng Y, Zhang J, Pan B, Hu Y, Wang Z
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
Zhang K, Zheng S, Wu J, He J, Ouyang Y, Ao C, Lang R, Jiang Y, Yang Y, Xiao H, Li Y, Li M, Wang H, Li C, Wu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
Insights into the function of ESCRT complex and LBPA in ASFV infection.
Barrado-Gil L, García-Dorival I, Galindo I, Alonso C, Cuesta-Geijo MÁ
Frontiers in cellular and infection microbiology 2023;13:1163569
Frontiers in cellular and infection microbiology 2023;13:1163569
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
Yi C, Wu S, Duan Q, Liu L, Li L, Luo Y, Wang A
PeerJ 2023;11:e15060
PeerJ 2023;11:e15060
The iron chelator deferriferrichrysin induces paraptosis via extracellular signal-related kinase activation in cancer cells.
Kinoshita N, Gessho M, Torii T, Ashida Y, Akamatsu M, Guo AK, Lee S, Katsuno T, Nakajima W, Budirahardja Y, Miyoshi D, Todokoro T, Ishida H, Nishikata T, Kawauchi K
Genes to cells : devoted to molecular & cellular mechanisms 2023 Sep;28(9):653-662
Genes to cells : devoted to molecular & cellular mechanisms 2023 Sep;28(9):653-662
Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.
Cao W, Dai S, Ruan W, Long T, Zeng Z, Lei S
Journal of cellular and molecular medicine 2023 Sep;27(17):2533-2546
Journal of cellular and molecular medicine 2023 Sep;27(17):2533-2546
Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434.
Wang M, Sun Y, Yuan D, Yue S, Yang Z
Experimental cell research 2023 Sep 15;430(2):113735
Experimental cell research 2023 Sep 15;430(2):113735
Extracellular Vesicle MicroRNAs From Corneal Stromal Stem Cell Enhance Stemness of Limbal Epithelial Stem Cells by Targeting the Notch Pathway.
Wang L, Xu X, Chen Q, Wei Y, Wei Z, Jin ZB, Liang Q
Investigative ophthalmology & visual science 2023 Sep 1;64(12):42
Investigative ophthalmology & visual science 2023 Sep 1;64(12):42
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
Chae CW, Yoon JH, Lim JR, Park JY, Cho JH, Jung YH, Choi GE, Lee HJ, Han HJ
Autophagy 2023 Oct;19(10):2752-2768
Autophagy 2023 Oct;19(10):2752-2768
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Mu X, Hu K, Wei A, Bai J, Feng L, Jiang J
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries.
Wang K, Frey N, Garcia A, Man K, Yang Y, Gualerzi A, Clemens ZJ, Bedoni M, LeDuc PR, Ambrosio F
ACS nano 2023 Oct 24;17(20):19640-19651
ACS nano 2023 Oct 24;17(20):19640-19651
Stress granules plug and stabilize damaged endolysosomal membranes.
Bussi C, Mangiarotti A, Vanhille-Campos C, Aylan B, Pellegrino E, Athanasiadi N, Fearns A, Rodgers A, Franzmann TM, Šarić A, Dimova R, Gutierrez MG
Nature 2023 Nov;623(7989):1062-1069
Nature 2023 Nov;623(7989):1062-1069
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Huang W, Zhang Y, Zheng B, Ling X, Wang G, Li L, Wang W, Pan M, Li X, Meng Y
International immunopharmacology 2023 Nov;124(Pt B):111017
International immunopharmacology 2023 Nov;124(Pt B):111017
Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles.
Fujioka Y, Otani K, Kodama T, Okada M, Yamawaki H
The Journal of veterinary medical science 2023 Nov 2;85(11):1157-1164
The Journal of veterinary medical science 2023 Nov 2;85(11):1157-1164
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
Lin L, Guo Z, He E, Long X, Wang D, Zhang Y, Guo W, Wei Q, He W, Wu W, Li J, Wo L, Hong D, Zheng J, He M, Zhao Q
Nature metabolism 2023 May;5(5):821-841
Nature metabolism 2023 May;5(5):821-841
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Li L, Cao J, Li S, Cui T, Ni J, Zhang H, Zhu Y, Mao J, Gao X, Midgley AC, Zhu M, Fan G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Wang F, Peters R, Jia J, Mudd M, Salemi M, Allers L, Javed R, Duque TLA, Paddar MA, Trosdal ES, Phinney B, Deretic V
Developmental cell 2023 May 22;58(10):866-884.e8
Developmental cell 2023 May 22;58(10):866-884.e8
Canocapavir Is a Novel Capsid Assembly Modulator Inducing a Conformational Change of the Linker Region of HBV Core Protein.
Zheng Y, Yang L, Yu L, Zhu Y, Wu Y, Zhang Z, Xia T, Deng Q
Viruses 2023 May 18;15(5)
Viruses 2023 May 18;15(5)
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
Huang X, Liu B, Guo S, Guo W, Liao K, Hu G, Shi W, Kuss M, Duryee MJ, Anderson DR, Lu Y, Duan B
Bioengineering & translational medicine 2023 Mar;8(2):e10420
Bioengineering & translational medicine 2023 Mar;8(2):e10420
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Wang Y, Zhang L, Lv L, Zhou Z, Xi H
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Li S, Yang K, Cao W, Guo R, Liu Z, Zhang J, Fan A, Huang Y, Ma C, Li L, Fan G
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Autophagy and exosomes coordinately mediate quercetin's protective effects on alcoholic liver disease.
Chen H, Liu J, Peng S, Yang G, Cheng X, Chen L, Zhang H, Zhao Y, Yao P, Tang Y
The Journal of nutritional biochemistry 2023 Jun;116:109332
The Journal of nutritional biochemistry 2023 Jun;116:109332
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
BMSC-derived extracellular vesicles promoted osteogenesis via Axin2 inhibition by delivering MiR-16-5p.
Duan J, Li H, Wang C, Yao J, Jin Y, Zhao J, Zhang Y, Liu M, Sun H
International immunopharmacology 2023 Jul;120:110319
International immunopharmacology 2023 Jul;120:110319
Phospho-RNA-Seq Highlights Specific Small RNA Profiles in Plasma Extracellular Vesicles.
Solaguren-Beascoa M, Gámez-Valero A, Escaramís G, Herrero-Lorenzo M, Ortiz AM, Minguet C, Gonzalo R, Bravo MI, Costa M, Martí E
International journal of molecular sciences 2023 Jul 19;24(14)
International journal of molecular sciences 2023 Jul 19;24(14)
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Yang S, Sun Y, Long M, Zhou X, Yuan M, Yang L, Luo W, Cheng Y, Zhang X, Jiang W, Chao J
Particle and fibre toxicology 2023 Jul 19;20(1):29
Particle and fibre toxicology 2023 Jul 19;20(1):29
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.
Irmer B, Efing J, Reitnauer LE, Angenendt A, Heinrichs S, Schubert A, Schulz M, Binder C, Tio J, Hansen U, Geyer C, Gerwing M, Bleckmann A, Menck K
Cell communication and signaling : CCS 2023 Jul 10;21(1):171
Cell communication and signaling : CCS 2023 Jul 10;21(1):171
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Li T, Ci Liu T, Liu N, Zhang M
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Macrophage-derived exosomal miR-195a-5p impairs tubular epithelial cells mitochondria in acute kidney injury mice.
Yuan L, Yang J, Liu F, Li L, Liu J, Chen Y, Cheng J, Lu Y, Yuan Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22691
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22691
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Liu D, Li X, Zeng B, Zhao Q, Chen H, Zhang Y, Chen Y, Wang J, Xing HR
Stem cell reviews and reports 2023 Jan;19(1):155-169
Stem cell reviews and reports 2023 Jan;19(1):155-169
NAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a "One-Stone-Two-Birds" manner.
Wu G, Su Q, Li J, Xue C, Zhu J, Cai Q, Huang J, Ji S, Cheng B, Ge H
Journal of nanobiotechnology 2023 Jan 5;21(1):7
Journal of nanobiotechnology 2023 Jan 5;21(1):7
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Izquierdo-Altarejos P, Cabrera-Pastor A, Martínez-García M, Sánchez-Huertas C, Hernández A, Moreno-Manzano V, Felipo V
Journal of neuroinflammation 2023 Jan 2;20(1):1
Journal of neuroinflammation 2023 Jan 2;20(1):1
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Ye Z, Xiong Y, Peng W, Wei W, Huang L, Yue J, Zhang C, Lin G, Huang F, Zhang L, Zheng S, Yue J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
Ayyar BV, Ettayebi K, Salmen W, Karandikar UC, Neill FH, Tenge VR, Crawford SE, Bieberich E, Prasad BVV, Atmar RL, Estes MK
Nature communications 2023 Feb 28;14(1):1148
Nature communications 2023 Feb 28;14(1):1148
Extracellular vesicles released from macrophages modulates interleukin-1β in astrocytic and neuronal cells.
Kodidela S, Sinha N, Kumar A, Zhou L, Godse S, Kumar S
Scientific reports 2023 Feb 21;13(1):3005
Scientific reports 2023 Feb 21;13(1):3005
Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells.
Wan Y, Yu Y, Yu C, Luo J, Wen S, Shen L, Wei G, Hua Y
Renal failure 2023 Dec;45(1):2221138
Renal failure 2023 Dec;45(1):2221138
Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3/pyroptosis axis: Toward a precision therapy.
Liu W, Liu A, Li X, Sun Z, Sun Z, Liu Y, Wang G, Huang D, Xiong H, Yu S, Zhang X, Fan C
Bioactive materials 2023 Dec;30:169-183
Bioactive materials 2023 Dec;30:169-183
Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.
Wang R, Li J, Fu Y, Li Y, Qi Y, Li C, Gao F, Li C
Biochemical pharmacology 2023 Dec;218:115874
Biochemical pharmacology 2023 Dec;218:115874
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Huang J, Ding M, Lu Y, Xu L, Zhang Y, Han S, Zhu X, Li Y, Chen P
Cell death & disease 2023 Dec 1;14(12):789
Cell death & disease 2023 Dec 1;14(12):789
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cancer communications (London, England) 2023 Aug;43(8):909-937
Exosomes-loaded electroconductive nerve dressing for nerve regeneration and pain relief against diabetic peripheral nerve injury.
Yang Q, Su S, Liu S, Yang S, Xu J, Zhong Y, Yang Y, Tian L, Tan Z, Wang J, Yu Z, Shi Z, Liang F
Bioactive materials 2023 Aug;26:194-215
Bioactive materials 2023 Aug;26:194-215
Prostate cancer cells synergistically defend against CD8(+) T cells by secreting exosomal PD-L1.
Li D, Zhou X, Xu W, Chen Y, Mu C, Zhao X, Yang T, Wang G, Wei L, Ma B
Cancer medicine 2023 Aug;12(15):16405-16415
Cancer medicine 2023 Aug;12(15):16405-16415
Exosomes Derived from Hypoxia-Cultured Human Adipose Stem Cells Alleviate Articular Chondrocyte Inflammaging and Post-Traumatic Osteoarthritis Progression.
Chang LH, Wu SC, Chen CH, Chen JW, Huang WC, Wu CW, Lin YS, Chen YJ, Chang JK, Ho ML
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Tumor-derived exosomes orchestrate the microRNA-128-3p/ELF4/CDX2 axis to facilitate the growth and metastasis of gastric cancer via delivery of LINC01091.
Wang Q, Zhang C, Cao S, Zhao H, Jiang R, Li Y
Cell biology and toxicology 2023 Apr;39(2):519-536
Cell biology and toxicology 2023 Apr;39(2):519-536
Chitosan Nerve Grafts Incorporated with SKP-SC-EVs Induce Peripheral Nerve Regeneration.
Zhou X, Yu M, Chen D, Deng C, Zhang Q, Gu X, Ding F
Tissue engineering and regenerative medicine 2023 Apr;20(2):309-322
Tissue engineering and regenerative medicine 2023 Apr;20(2):309-322
Exosomal lipid PI4P regulates small extracellular vesicle secretion by modulating intraluminal vesicle formation.
Jin X, Xia T, Luo S, Zhang Y, Xia Y, Yin H
Journal of extracellular vesicles 2023 Apr;12(4):e12319
Journal of extracellular vesicles 2023 Apr;12(4):e12319
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
LncRNA H19-rich extracellular vesicles derived from gastric cancer stem cells facilitate tumorigenicity and metastasis via mediating intratumor communication network.
Zhao H, Jiang R, Zhang C, Feng Z, Wang X
Journal of translational medicine 2023 Apr 1;21(1):238
Journal of translational medicine 2023 Apr 1;21(1):238
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Li J, Zhao B, Dai Y, Zhang X, Chen Y, Wu X
Oxidative medicine and cellular longevity 2022;2022:9042345
Oxidative medicine and cellular longevity 2022;2022:9042345
Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection.
Ma D, Zhang QY, Rong HM, Zhai K, Tong ZH
Journal of immunology research 2022;2022:5187166
Journal of immunology research 2022;2022:5187166
Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes.
Zhao Y, Huang Y, Liu H, Tan K, Wang R, Jia L, Li W
Stem cells international 2022;2022:4185972
Stem cells international 2022;2022:4185972
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
Chen K, Wang Q, Liu X, Wang F, Yang Y, Tian X
International journal of biological sciences 2022;18(3):1220-1237
International journal of biological sciences 2022;18(3):1220-1237
Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.
Xiao Y, Liang J, Witwer KW, Zhang Y, Wang Q, Yin H
Frontiers in immunology 2022;13:955175
Frontiers in immunology 2022;13:955175
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Kutchy NA, Ma R, Liu Y, Buch S, Hu G
Frontiers in pharmacology 2022;13:819516
Frontiers in pharmacology 2022;13:819516
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
Zhao J, Chen J, Zhu W, Qi XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
Wang Y, Liu S, Li L, Li L, Zhou X, Wan M, Lou P, Zhao M, Lv K, Yuan Y, Chen Y, Lu Y, Cheng J, Liu J
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Luo L, Gong J, Wang Z, Liu Y, Cao J, Qin J, Zuo R, Zhang H, Wang S, Zhao P, Yang D, Zhang M, Wang Y, Zhang J, Zhou Y, Li C, Ni B, Tian Z, Liu M
Bioactive materials 2022 Sep;15:29-43
Bioactive materials 2022 Sep;15:29-43
Extracellular vesicle fusion visualized by cryo-electron microscopy.
Morandi MI, Busko P, Ozer-Partuk E, Khan S, Zarfati G, Elbaz-Alon Y, Abou Karam P, Napso Shogan T, Ginini L, Gil Z, Regev-Rudzki N, Avinoam O
PNAS nexus 2022 Sep;1(4):pgac156
PNAS nexus 2022 Sep;1(4):pgac156
Vasorin-containing small extracellular vesicles retard intervertebral disc degeneration utilizing an injectable thermoresponsive delivery system.
Liao Z, Ke W, Liu H, Tong B, Wang K, Feng X, Hua W, Wang B, Song Y, Luo R, Liang H, Zhang W, Zhao K, Li S, Yang C
Journal of nanobiotechnology 2022 Sep 19;20(1):420
Journal of nanobiotechnology 2022 Sep 19;20(1):420
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2.
Qian C, Wang Y, Ji Y, Chen D, Wang C, Zhang G, Wang Y
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Ischemia-Reperfusion Injury and Promote Survival of Skin Flaps in Rats.
Niu Q, Yang Y, Li D, Guo W, Wang C, Xu H, Feng Z, Han Z
Life (Basel, Switzerland) 2022 Oct 9;12(10)
Life (Basel, Switzerland) 2022 Oct 9;12(10)
Extracellular vesicles microRNA-592 of melanoma stem cells promotes metastasis through activation of MAPK/ERK signaling pathway by targeting PTPN7 in non-stemness melanoma cells.
Zhang Y, Chen Y, Shi L, Li J, Wan W, Li B, Liu D, Li X, Chen Y, Xiang M, Chen H, Zeng B, Xing HR, Wang J
Cell death discovery 2022 Oct 27;8(1):428
Cell death discovery 2022 Oct 27;8(1):428
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Li X, Liu D, Chen H, Zeng B, Zhao Q, Zhang Y, Chen Y, Wang J, Xing HR
Biological research 2022 Oct 1;55(1):29
Biological research 2022 Oct 1;55(1):29
Cancer-derived exosomal circ_0038138 enhances glycolysis, growth, and metastasis of gastric adenocarcinoma via the miR-198/EZH2 axis.
Zheng Y, Li P, Ma J, Yang C, Dai S, Zhao C
Translational oncology 2022 Nov;25:101479
Translational oncology 2022 Nov;25:101479
HBV induced the discharge of intrinsic antiviral miRNAs in HBV-replicating hepatocytes via extracellular vesicles to facilitate its replication.
Chu Q, Li J, Chen J, Yuan Z
The Journal of general virology 2022 May;103(5)
The Journal of general virology 2022 May;103(5)
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes.
Bub A, Brenna S, Alawi M, Kügler P, Gui Y, Kretz O, Altmeppen H, Magnus T, Puig B
Cellular and molecular life sciences : CMLS 2022 May 31;79(6):329
Cellular and molecular life sciences : CMLS 2022 May 31;79(6):329
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
Chen D, Jiang X
Experimental cell research 2022 May 1;414(1):113066
Experimental cell research 2022 May 1;414(1):113066
In Vitro and In Vivo Analysis of Extracellular Vesicle-Mediated Metastasis Using a Bright, Red-Shifted Bioluminescent Reporter Protein.
Perez GI, Broadbent D, Zarea AA, Dolgikh B, Bernard MP, Withrow A, McGill A, Toomajian V, Thampy LK, Harkema J, Walker JR, Kirkland TA, Bachmann MH, Schmidt J, Kanada M
Advanced genetics (Hoboken, N.J.) 2022 Mar;3(1):2100055
Advanced genetics (Hoboken, N.J.) 2022 Mar;3(1):2100055
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Ren X, Lv J, Wang N, Liu J, Gao C, Wu X, Yu Y, Teng Q, Dong W, Kong H, Kong L
Diabetes research and clinical practice 2022 Mar;185:109788
Diabetes research and clinical practice 2022 Mar;185:109788
Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity.
Ortiz-Bonilla CJ, Uccello TP, Gerber SA, Lord EM, Messing EM, Lee YF
International journal of molecular sciences 2022 Mar 8;23(6)
International journal of molecular sciences 2022 Mar 8;23(6)
Serum exosomal proteomics analysis of lung adenocarcinoma to discover new tumor markers.
Liu S, Tian W, Ma Y, Li J, Yang J, Li B
BMC cancer 2022 Mar 15;22(1):279
BMC cancer 2022 Mar 15;22(1):279
Recruitment of DNA to tumor-derived microvesicles.
Clancy JW, Sheehan CS, Boomgarden AC, D'Souza-Schorey C
Cell reports 2022 Mar 1;38(9):110443
Cell reports 2022 Mar 1;38(9):110443
Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.
Ho ML, Hsu CJ, Wu CW, Chang LH, Chen JW, Chen CH, Huang KC, Chang JK, Wu SC, Shao PL
Biomedicines 2022 Jul 21;10(7)
Biomedicines 2022 Jul 21;10(7)
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Zhou H, Shen X, Yan C, Xiong W, Ma Z, Tan Z, Wang J, Li Y, Liu J, Duan A, Liu F
Stem cell research & therapy 2022 Jul 16;13(1):322
Stem cell research & therapy 2022 Jul 16;13(1):322
Tsc2 mutation induces renal tubular cell nonautonomous disease.
Kumar P, Zadjali F, Yao Y, Johnson D, Siroky B, Astrinidis A, Vogel P, Gross KW, Bissler JJ
Genes & diseases 2022 Jan;9(1):187-200
Genes & diseases 2022 Jan;9(1):187-200
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
Carrascal M, Areny-Balagueró A, de-Madaria E, Cárdenas-Jaén K, García-Rayado G, Rivera R, Martin Mateos RM, Pascual-Moreno I, Gironella M, Abian J, Closa D
The Journal of pathology 2022 Jan;256(1):83-92
The Journal of pathology 2022 Jan;256(1):83-92
In Vivo Visualized Tracking of Tumor-Derived Extracellular Vesicles Using CRISPR-Cas9 System.
Ye Y, Shi Q, Yang T, Xie F, Zhang X, Xu B, Fang J, Chen J, Zhang Y, Li J
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221085370
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221085370
A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles.
Kanada M, Linenfelser L, Cox E, Gilad AA
Pharmaceutics 2022 Feb 22;14(3)
Pharmaceutics 2022 Feb 22;14(3)
Tumor-derived extracellular vesicles confer 5-fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery.
Zhang S, Liu S, Ren J, Zhang H, Chen S, Chen Y, Zhang S, Chen W, Xu C, Zhong S, Liu S, Lin C
Molecular carcinogenesis 2022 Dec;61(12):1177-1190
Molecular carcinogenesis 2022 Dec;61(12):1177-1190
Improving the circulation time and renal therapeutic potency of extracellular vesicles using an endogenous ligand binding strategy.
Liu S, Lv K, Wang Y, Lou P, Zhou P, Wang C, Li L, Liao G, Zhang Y, Chen Y, Cheng J, Lu Y, Liu J
Journal of controlled release : official journal of the Controlled Release Society 2022 Dec;352:1009-1023
Journal of controlled release : official journal of the Controlled Release Society 2022 Dec;352:1009-1023
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Gao Y, Zheng X, Chang B, Lin Y, Huang X, Wang W, Ding S, Zhan W, Wang S, Xiao B, Huo L, Yu Y, Chen Y, Gong R, Wu Y, Zhang R, Zhong L, Wang X, Chen Q, Gao S, Jiang Z, Wei D, Kang T
Cell research 2022 Dec;32(12):1086-1104
Cell research 2022 Dec;32(12):1086-1104
Effect of plasma-derived extracellular vesicles on angiogenesis and the ensuing proliferative diabetic retinopathy through a miR-30b-dependent mechanism.
Wang P, Li C, Deng Y, Yu Q, Meng X, Jiang T, Wang Q, Fu Y
Diabetology & metabolic syndrome 2022 Dec 10;14(1):188
Diabetology & metabolic syndrome 2022 Dec 10;14(1):188
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.
Li B, Huang J, Liu J, He F, Wen F, Yang C, Wang W, Wu T, Zhao T, Yao J, Liu S, Qiu Y, Fang M, Zeng J, Wu Z
Bioorganic chemistry 2022 Apr;121:105651
Bioorganic chemistry 2022 Apr;121:105651
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
Zhao Q, Chen H, Li X, Zeng B, Sun Z, Liu D, Chen Y, Zhang Y, Rosie Xing H, Wang J
Cell death discovery 2022 Apr 9;8(1):188
Cell death discovery 2022 Apr 9;8(1):188
Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles.
Kumar P, Zadjali F, Yao Y, Siroky B, Astrinidis A, Gross KW, Bissler JJ
Frontiers in physiology 2021;12:630933
Frontiers in physiology 2021;12:630933
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Xiong J, Wu L, Huang L, Wu C, Liu Z, Deng W, Ma S, Zhou Z, Yu H, Cao K
Frontiers in oncology 2021;11:718876
Frontiers in oncology 2021;11:718876
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Huang J, Yu M, Yin W, Liang B, Li A, Li J, Li X, Zhao S, Liu F
Bioactive materials 2021 Sep;6(9):2841-2853
Bioactive materials 2021 Sep;6(9):2841-2853
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration.
Yu H, Yang X, Xiao X, Xu M, Yang Y, Xue C, Li X, Wang S, Zhao RC
Aging and disease 2021 Sep;12(6):1423-1437
Aging and disease 2021 Sep;12(6):1423-1437
A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization.
Liu W, Yu M, Chen F, Wang L, Ye C, Chen Q, Zhu Q, Xie D, Shao M, Yang L
Journal of nanobiotechnology 2021 Sep 7;19(1):269
Journal of nanobiotechnology 2021 Sep 7;19(1):269
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Liao Z, Liu H, Ma L, Lei J, Tong B, Li G, Ke W, Wang K, Feng X, Hua W, Li S, Yang C
ACS nano 2021 Sep 28;15(9):14709-14724
ACS nano 2021 Sep 28;15(9):14709-14724
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Sun NN, Zhang Y, Huang WH, Zheng BJ, Jin SY, Li X, Meng Y
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Neddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles.
Fei X, Li Z, Yang D, Kong X, Lu X, Shen Y, Li X, Xie S, Wang J, Zhao Y, Sun Y, Zhang J, Ye Z, Wang J, Cai Z
Journal of extracellular vesicles 2021 Oct;10(12):e12153
Journal of extracellular vesicles 2021 Oct;10(12):e12153
Tenascin-C expression in the lymph node pre-metastatic niche in muscle-invasive bladder cancer.
Silvers CR, Messing EM, Miyamoto H, Lee YF
British journal of cancer 2021 Nov;125(10):1399-1407
British journal of cancer 2021 Nov;125(10):1399-1407
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Gao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
Lin L, Wang H, Guo W, He E, Huang K, Zhao Q
Cellular signalling 2021 Jun;82:109935
Cellular signalling 2021 Jun;82:109935
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Duan A, Shen K, Li B, Li C, Zhou H, Kong R, Shao Y, Qin J, Yuan T, Ji J, Guo W, Wang X, Xue T, Li L, Huang X, Sun Y, Cai Z, Liu W, Liu F
Stem cell research & therapy 2021 Jul 28;12(1):427
Stem cell research & therapy 2021 Jul 28;12(1):427
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta Delivery.
Zou X, Yuan M, Zhang T, Zheng N, Wu Z
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):176-190
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):176-190
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Mitochondrial Damage and Inflammation by Stabilizing Mitochondrial DNA.
Zhao M, Liu S, Wang C, Wang Y, Wan M, Liu F, Gong M, Yuan Y, Chen Y, Cheng J, Lu Y, Liu J
ACS nano 2021 Jan 26;15(1):1519-1538
ACS nano 2021 Jan 26;15(1):1519-1538
RAB31 marks and controls an ESCRT-independent exosome pathway.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, Zhang R, Wu Y, Gao S, Kang T
Cell research 2021 Feb;31(2):157-177
Cell research 2021 Feb;31(2):157-177
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Cao W, Zeng Z, He Z, Lei S
Aging 2021 Feb 26;13(5):7120-7132
Aging 2021 Feb 26;13(5):7120-7132
Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism.
Ochiai-Homma F, Kuribayashi-Okuma E, Tsurutani Y, Ishizawa K, Fujii W, Odajima K, Kawagoe M, Tomomitsu Y, Murakawa M, Asakawa S, Hirohama D, Nagura M, Arai S, Yamazaki O, Tamura Y, Fujigaki Y, Nishikawa T, Shibata S
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Dec;44(12):1557-1567
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Dec;44(12):1557-1567
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Yang J, Hu Y, Wang L, Sun X, Yu L, Guo W
Bioengineered 2021 Dec;12(2):11007-11017
Bioengineered 2021 Dec;12(2):11007-11017
Extracellular vesicles derived from lipoaspirate fluid promote fat graft survival.
Nie F, Ding P, Zhang C, Zhao Z, Bi H
Adipocyte 2021 Dec;10(1):293-309
Adipocyte 2021 Dec;10(1):293-309
Surface Nanosieving Polyether Sulfone Particles with Graphene Oxide Encapsulation for the Negative Isolation toward Extracellular Vesicles.
Li Y, Yang K, Yuan H, Zhang W, Sui Z, Wang N, Lin H, Zhang L, Zhang Y
Analytical chemistry 2021 Dec 21;93(50):16835-16844
Analytical chemistry 2021 Dec 21;93(50):16835-16844
Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway.
Zhao F, Zheng T, Gong W, Wu J, Xie H, Li W, Zhang R, Liu P, Liu J, Wu X, Zhao Y, Ren J
Cell death & disease 2021 Aug 27;12(9):815
Cell death & disease 2021 Aug 27;12(9):815
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration.
Li Q, Yu H, Sun M, Yang P, Hu X, Ao Y, Cheng J
Acta biomaterialia 2021 Apr 15;125:253-266
Acta biomaterialia 2021 Apr 15;125:253-266
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G
Journal of extracellular vesicles 2020;9(1):1716513
Journal of extracellular vesicles 2020;9(1):1716513
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Chen S, Wang Y, Liao L, Meng L, Li J, Shi C, Han H, Zheng X, Shen H
Stem cells international 2020;2020:8861557
Stem cells international 2020;2020:8861557
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425
Theranostics 2020;10(1):411-425
Plasma Exosomal miRNA Expression Profile as Oxaliplatin-Based Chemoresistant Biomarkers in Colorectal Adenocarcinoma.
Han J, Sun W, Liu R, Zhou Z, Zhang H, Chen X, Ba Y
Frontiers in oncology 2020;10:1495
Frontiers in oncology 2020;10:1495
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Matic S, D'Souza DH, Wu T, Pangloli P, Dia VP
Immunological investigations 2020 Oct;49(7):711-725
Immunological investigations 2020 Oct;49(7):711-725
Exosomes derived from TSG-6 modified mesenchymal stromal cells attenuate scar formation during wound healing.
Jiang L, Zhang Y, Liu T, Wang X, Wang H, Song H, Wang W
Biochimie 2020 Oct;177:40-49
Biochimie 2020 Oct;177:40-49
Profilin 2 promotes growth, metastasis, and angiogenesis of small cell lung cancer through cancer-derived exosomes.
Cao Q, Liu Y, Wu Y, Hu C, Sun L, Wang J, Li C, Guo M, Liu X, Lv J, Huo X, Yue J, Du X, Chen Z
Aging 2020 Nov 21;12(24):25981-25999
Aging 2020 Nov 21;12(24):25981-25999
Isolation of extracellular vesicles from intestinal tissue in a mouse model of intestinal ischemia/reperfusion injury.
Chen XD, Zhao J, Yan Z, Zhou BW, Huang WF, Liu WF, Li C, Liu KX
BioTechniques 2020 May;68(5):257-262
BioTechniques 2020 May;68(5):257-262
DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses.
Hitomi K, Okada R, Loo TM, Miyata K, Nakamura AJ, Takahashi A
International journal of molecular sciences 2020 May 25;21(10)
International journal of molecular sciences 2020 May 25;21(10)
Tuberous Sclerosis Complex Axis Controls Renal Extracellular Vesicle Production and Protein Content.
Zadjali F, Kumar P, Yao Y, Johnson D, Astrinidis A, Vogel P, Gross KW, Bissler JJ
International journal of molecular sciences 2020 Mar 3;21(5)
International journal of molecular sciences 2020 Mar 3;21(5)
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
He J, He J, Min L, He Y, Guan H, Wang J, Peng X
International journal of cancer 2020 Feb 15;146(4):1052-1063
International journal of cancer 2020 Feb 15;146(4):1052-1063
Circulating exosomal small RNAs are promising non-invasive diagnostic biomarkers for gastric cancer.
Ge L, Zhang N, Li D, Wu Y, Wang H, Wang J
Journal of cellular and molecular medicine 2020 Dec;24(24):14502-14513
Journal of cellular and molecular medicine 2020 Dec;24(24):14502-14513
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Sha L, Ma D, Chen C
Aging 2020 Dec 13;12(23):23598-23608
Aging 2020 Dec 13;12(23):23598-23608
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Mercier V, Larios J, Molinard G, Goujon A, Matile S, Gruenberg J, Roux A
Nature cell biology 2020 Aug;22(8):947-959
Nature cell biology 2020 Aug;22(8):947-959
Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis.
Xiang E, Han B, Zhang Q, Rao W, Wang Z, Chang C, Zhang Y, Tu C, Li C, Wu D
Stem cell research & therapy 2020 Aug 3;11(1):336
Stem cell research & therapy 2020 Aug 3;11(1):336
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
Yu M, Liu W, Li J, Lu J, Lu H, Jia W, Liu F
Stem cell research & therapy 2020 Aug 12;11(1):350
Stem cell research & therapy 2020 Aug 12;11(1):350
KLF4-mediated upregulation of CD9 and CD81 suppresses hepatocellular carcinoma development via JNK signaling.
Li Y, Yu S, Li L, Chen J, Quan M, Li Q, Gao Y
Cell death & disease 2020 Apr 29;11(4):299
Cell death & disease 2020 Apr 29;11(4):299
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Wang D, Hao C, Zhang L, Zhang J, Liu S, Li Y, Qu Y, Zhao Y, Huang R, Wei J, Yao W
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env(+) tissues.
Zou X, Yuan M, Zhang T, Wei H, Xu S, Jiang N, Zheng N, Wu Z
Theranostics 2019;9(19):5657-5671
Theranostics 2019;9(19):5657-5671
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, Hua W, Zhang Y, Wu X, Yang C
Theranostics 2019;9(14):4084-4100
Theranostics 2019;9(14):4084-4100
Cocktail Strategy Based on NK Cell-Derived Exosomes and Their Biomimetic Nanoparticles for Dual Tumor Therapy.
Wang G, Hu W, Chen H, Shou X, Ye T, Xu Y
Cancers 2019 Oct 14;11(10)
Cancers 2019 Oct 14;11(10)
O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
Liu L, Li L, Ma C, Shi Y, Liu C, Xiao Z, Zhang Y, Tian F, Gao Y, Zhang J, Ying W, Wang PG, Zhang L
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
Exosomes derived from human CD34(+) stem cells transfected with miR-26a prevent glucocorticoid-induced osteonecrosis of the femoral head by promoting angiogenesis and osteogenesis.
Zuo R, Kong L, Wang M, Wang W, Xu J, Chai Y, Guan J, Kang Q
Stem cell research & therapy 2019 Nov 15;10(1):321
Stem cell research & therapy 2019 Nov 15;10(1):321
Ovarian cancer circulating extracelluar vesicles promote coagulation and have a potential in diagnosis: an iTRAQ based proteomic analysis.
Zhang W, Peng P, Ou X, Shen K, Wu X
BMC cancer 2019 Nov 12;19(1):1095
BMC cancer 2019 Nov 12;19(1):1095
Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8(+) T Cell Responses.
Zhang F, Li R, Yang Y, Shi C, Shen Y, Lu C, Chen Y, Zhou W, Lin A, Yu L, Zhang W, Xue Z, Wang J, Cai Z
Immunity 2019 Mar 19;50(3):738-750.e7
Immunity 2019 Mar 19;50(3):738-750.e7
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Wei S, Zheng Y, Jiang Y, Li X, Geng J, Shen Y, Li Q, Wang X, Zhao C, Chen Y, Qian Z, Zhou J, Li W
EBioMedicine 2019 Jun;44:182-193
EBioMedicine 2019 Jun;44:182-193
Cluster of Differentiation 46 Is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28).
Kuroda H, Tachikawa M, Yagi Y, Umetsu M, Nurdin A, Miyauchi E, Watanabe M, Uchida Y, Terasaki T
Molecular pharmaceutics 2019 Jan 7;16(1):292-304
Molecular pharmaceutics 2019 Jan 7;16(1):292-304
Microvesicle-Mediated Delivery of Minicircle DNA Results in Effective Gene-Directed Enzyme Prodrug Cancer Therapy.
Kanada M, Kim BD, Hardy JW, Ronald JA, Bachmann MH, Bernard MP, Perez GI, Zarea AA, Ge TJ, Withrow A, Ibrahim SA, Toomajian V, Gambhir SS, Paulmurugan R, Contag CH
Molecular cancer therapeutics 2019 Dec;18(12):2331-2342
Molecular cancer therapeutics 2019 Dec;18(12):2331-2342
Detection of exosomal tyrosine receptor kinase B as a potential biomarker in ovarian cancer.
Li W, Lu Y, Yu X, Yong M, Ma D, Gao Q
Journal of cellular biochemistry 2019 Apr;120(4):6361-6369
Journal of cellular biochemistry 2019 Apr;120(4):6361-6369
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α(1)-antitrypsin disposal.
Khodayari N, Oshins R, Alli AA, Tuna KM, Holliday LS, Krotova K, Brantly M
The Journal of biological chemistry 2019 Apr 19;294(16):6240-6252
The Journal of biological chemistry 2019 Apr 19;294(16):6240-6252
Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.
Huang H, Zheng X, Cai C, Yao Z, Lu S, Meng X, Miao Y, He Z, Cai C, Zou F
Biochemical and biophysical research communications 2018 Sep 3;503(1):242-248
Biochemical and biophysical research communications 2018 Sep 3;503(1):242-248
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response.
Mittal E, Skowyra ML, Uwase G, Tinaztepe E, Mehra A, Köster S, Hanson PI, Philips JA
mBio 2018 Nov 27;9(6)
mBio 2018 Nov 27;9(6)
CD8α(+)CD11c(+) Extracellular Vesicles in the Lungs Control Immune Homeostasis of the Respiratory Tract via TGF-β1 and IL-10.
Wan S, Wang S, Weng L, Zhang G, Lin Z, Fei X, Zhang F, Yang F, Wang J, Cai Z
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1651-1660
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1651-1660
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling.
Ringuette Goulet C, Bernard G, Tremblay S, Chabaud S, Bolduc S, Pouliot F
Molecular cancer research : MCR 2018 Jul;16(7):1196-1204
Molecular cancer research : MCR 2018 Jul;16(7):1196-1204
Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity.
Yao Z, Qiao Y, Li X, Chen J, Ding J, Bai L, Shen F, Shi B, Liu J, Peng L, Li J, Yuan Z
Journal of virology 2018 Dec 15;92(24)
Journal of virology 2018 Dec 15;92(24)
Circulating Exosomal miR-17-5p and miR-92a-3p Predict Pathologic Stage and Grade of Colorectal Cancer.
Fu F, Jiang W, Zhou L, Chen Z
Translational oncology 2018 Apr;11(2):221-232
Translational oncology 2018 Apr;11(2):221-232
Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.
Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF
Oncotarget 2017 Oct 31;8(53):91199-91208
Oncotarget 2017 Oct 31;8(53):91199-91208
Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication.
Haque S, Sinha N, Ranjit S, Midde NM, Kashanchi F, Kumar S
Scientific reports 2017 Nov 23;7(1):16120
Scientific reports 2017 Nov 23;7(1):16120
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
Takahashi A, Okada R, Nagao K, Kawamata Y, Hanyu A, Yoshimoto S, Takasugi M, Watanabe S, Kanemaki MT, Obuse C, Hara E
Nature communications 2017 May 16;8:15287
Nature communications 2017 May 16;8:15287
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Bonjoch L, Gironella M, Iovanna JL, Closa D
Scientific reports 2017 Jun 9;7(1):3143
Scientific reports 2017 Jun 9;7(1):3143
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Takasugi M, Okada R, Takahashi A, Virya Chen D, Watanabe S, Hara E
Nature communications 2017 Jun 6;8:15729
Nature communications 2017 Jun 6;8:15729
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Zhang J, Lu S, Zhou Y, Meng K, Chen Z, Cui Y, Shi Y, Wang T, He QY
Proteomics 2017 Jul;17(13-14)
Proteomics 2017 Jul;17(13-14)
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Bonjoch L, Casas V, Carrascal M, Closa D
The Journal of pathology 2016 Oct;240(2):235-45
The Journal of pathology 2016 Oct;240(2):235-45
Regulation of exosomes released from normal ovarian epithelial cells and ovarian cancer cells.
Zhang W, Yang J, Cao D, You Y, Shen K, Peng P
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct 6;
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct 6;
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance.
Jiang L, Shen Y, Guo D, Yang D, Liu J, Fei X, Yang Y, Zhang B, Lin Z, Yang F, Wang X, Wang K, Wang J, Cai Z
Nature communications 2016 Oct 10;7:13045
Nature communications 2016 Oct 10;7:13045
Characterization of exosomes derived from ovarian cancer cells and normal ovarian epithelial cells by nanoparticle tracking analysis.
Zhang W, Peng P, Kuang Y, Yang J, Cao D, You Y, Shen K
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):4213-21
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):4213-21
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K
Journal of proteomics 2013 Mar 27;80:171-82
Journal of proteomics 2013 Mar 27;80:171-82
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Li J, Liu K, Liu Y, Xu Y, Zhang F, Yang H, Liu J, Pan T, Chen J, Wu M, Zhou X, Yuan Z
Nature immunology 2013 Aug;14(8):793-803
Nature immunology 2013 Aug;14(8):793-803
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.
Hopp K, Ward CJ, Hommerding CJ, Nasr SH, Tuan HF, Gainullin VG, Rossetti S, Torres VE, Harris PC
The Journal of clinical investigation 2012 Nov;122(11):4257-73
The Journal of clinical investigation 2012 Nov;122(11):4257-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12422-1-AP(ALIX; AIP1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using PDCD6IP antibody 12422-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDCD6IP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDCD6IP. This antibody recognizes human,mouse,rat antigen. The PDCD6IP antibody has been validated for the following applications: ELISA, IF, IP, WB analysis.
