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LearnH00055294-M02
antibody from Novus Biologicals
Targeting: FBXW7
AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- H00055294-M02 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00055294-M02, RRID:AB_608430
- Product name
- Mouse Monoclonal FBXW7/Cdc4 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. FBXW7 - F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The role of FBXW7, a cell-cycle regulator, as a predictive marker of recurrence of gastrointestinal stromal tumors.
FBXW7 expression affects the response to chemoradiotherapy and overall survival among patients with oral squamous cell carcinoma: A single-center retrospective study.
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease.
F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
Genomic and molecular characterization of esophageal squamous cell carcinoma.
FBXW7 mediates chemotherapeutic sensitivity and prognosis in NSCLCs.
The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance.
Structural basis for a reciprocal regulation between SCF and CSN.
Koga Y, Iwatsuki M, Yamashita K, Kiyozumi Y, Kurashige J, Masuda T, Eto K, Iwagami S, Harada K, Ishimoto T, Baba Y, Yoshida N, Miyanari N, Takamori H, Ajani JA, Baba H
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2019 Nov;22(6):1100-1108
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2019 Nov;22(6):1100-1108
FBXW7 expression affects the response to chemoradiotherapy and overall survival among patients with oral squamous cell carcinoma: A single-center retrospective study.
Arita H, Nagata M, Yoshida R, Matsuoka Y, Hirosue A, Kawahara K, Sakata J, Nakashima H, Kojima T, Toya R, Murakami R, Hiraki A, Shinohara M, Nakayama H
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Oct;39(10):1010428317731771
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Oct;39(10):1010428317731771
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Yao S, Xu F, Chen Y, Ge Y, Zhang F, Huang H, Li L, Lin D, Luo X, Xu J, Luo D, Zhu X, Liu Y
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):10
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):10
Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease.
Hua J, Ding T, Yang L
OncoTargets and therapy 2016;9:6573-6579
OncoTargets and therapy 2016;9:6573-6579
F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
Yumimoto K, Akiyoshi S, Ueo H, Sagara Y, Onoyama I, Ueo H, Ohno S, Mori M, Mimori K, Nakayama KI
The Journal of clinical investigation 2015 Feb;125(2):621-35
The Journal of clinical investigation 2015 Feb;125(2):621-35
Genomic and molecular characterization of esophageal squamous cell carcinoma.
Lin DC, Hao JJ, Nagata Y, Xu L, Shang L, Meng X, Sato Y, Okuno Y, Varela AM, Ding LW, Garg M, Liu LZ, Yang H, Yin D, Shi ZZ, Jiang YY, Gu WY, Gong T, Zhang Y, Xu X, Kalid O, Shacham S, Ogawa S, Wang MR, Koeffler HP
Nature genetics 2014 May;46(5):467-73
Nature genetics 2014 May;46(5):467-73
FBXW7 mediates chemotherapeutic sensitivity and prognosis in NSCLCs.
Yokobori T, Yokoyama Y, Mogi A, Endoh H, Altan B, Kosaka T, Yamaki E, Yajima T, Tomizawa K, Azuma Y, Onozato R, Miyazaki T, Tanaka S, Kuwano H
Molecular cancer research : MCR 2014 Jan;12(1):32-7
Molecular cancer research : MCR 2014 Jan;12(1):32-7
The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance.
Yang S, Wang B, Humphries F, Hogan AE, O'Shea D, Moynagh PN
Immunity 2014 Dec 18;41(6):973-87
Immunity 2014 Dec 18;41(6):973-87
Structural basis for a reciprocal regulation between SCF and CSN.
Enchev RI, Scott DC, da Fonseca PC, Schreiber A, Monda JK, Schulman BA, Peter M, Morris EP
Cell reports 2012 Sep 27;2(3):616-27
Cell reports 2012 Sep 27;2(3):616-27
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: FBXW7/Cdc4 Antibody (3D1) [H00055294-M02] - Detection limit for recombinant GST tagged FBXW7 is approximately 0.1ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FBXW7/Cdc4 Antibody (3D1) [H00055294-M02] - Analysis of monoclonal antibody to FBXW7 on formalin-fixed paraffin-embedded human lung. Antibody concentration 3 ug/ml.
