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LearnMA1-072
antibody from Invitrogen Antibodies
Targeting: OGT
FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1
Western blot
Immunocytochemistry Immunoprecipitation Immunohistochemistry Chromatin Immunoprecipitation Other assayAntibody data
- Antibody Data
- Antigen structure
- References [110]
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- Validations
- Western blot [1]
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- Product number
- MA1-072 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-O-linked N-acetylglucosamine (O-GlcNAc) Monoclonal Antibody (RL2)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA1-072 detects nuclear pore complex (NPC), cytoplasmic and intranuclear O-linked glycoproteins from human, mouse, virus and rat tissues. MA1-072 has been successfully used in Western blot, immunofluorescence and immunoprecipitation procedures. By Western blot, this antibody recognizes up to eight different proteins from the NPC of approximately 210, 180, 145, 100, 63, 58, 54 and 45 kDa as well as other O-linked glycoproteins outside of the NPC. Immunofluorescence staining of the NPC with MA1-072 primarily labels NPC O-linked glycoproteins and has been successfully used on a wide variety of mammalian cells. Labeling occurs at the NPC, with most of the labeling at the cytoplasmic and/or nucleoplasmic margins, as well as within the nucleus. The MA1-072 immunogen is pore complex-lamina fraction purified from rat liver nuclear envelopes.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- RL2
- Vial size
- 100 µL
- Concentration
- 2 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Protein O-GlcNAc Modification Increases in White Blood Cells After a Single Bout of Physical Exercise.
Changes in Protein O-GlcNAcylation During Mouse Epididymal Sperm Maturation.
Synaptic protein changes after a chronic period of sensorimotor perturbation in adult rats: a potential role of phosphorylation/O-GlcNAcylation interplay.
O-Linked N-Acetylglucosamine Transiently Elevates in HeLa Cells during Mitosis.
Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice.
Mitochondrial O-GlcNAc Transferase (mOGT) Regulates Mitochondrial Structure, Function, and Survival in HeLa Cells.
LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice.
A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis.
Exercise training increases protein O-GlcNAcylation in rat skeletal muscle.
O-GlcNAcylation is a key modulator of skeletal muscle sarcomeric morphometry associated to modulation of protein-protein interactions.
Downregulation of O-linked N-acetylglucosamine transferase by RNA interference decreases MMP9 expression in human esophageal cancer cells.
Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation.
Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer's disease.
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells.
4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition.
Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18.
O-GlcNAcylation enhances anaplastic thyroid carcinoma malignancy.
Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration.
O-GlcNAc cycling enzymes control vascular development of the placenta by modulating the levels of HIF-1α.
Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling.
Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis.
Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle.
O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster.
Conserved nutrient sensor O-GlcNAc transferase is integral to C. elegans pathogen-specific immunity.
X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body.
Inhibition of mTOR affects protein stability of OGT.
Phospho-GlcNAc modulation of slow MLC2 during soleus atrophy through a multienzymatic and sarcomeric complex.
OGA heterozygosity suppresses intestinal tumorigenesis in Apc(min/+) mice.
Oral glucosamine sulfate supplementation does not induce endoplasmic reticulum stress or activate the unfolded protein response in circulating leukocytes of human subjects.
Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy.
Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers.
Hexosamine biosynthesis is a possible mechanism underlying hypoxia's effects on lipid metabolism in human adipocytes.
Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.
A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2.
Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400.
CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease.
Potential regulation of human muscle plasticity by MLC2 post-translational modifications during bed rest and countermeasures.
Requirement of decreased O-GlcNAc glycosylation of Mef2D for its recruitment to the myogenin promoter.
The increase in O-linked N-acetylglucosamine protein modification stimulates chondrogenic differentiation both in vitro and in vivo.
Rescue of the transcription factors Sp1 and NFI in human skin keratinocytes through a feeder-layer-dependent suppression of the proteasome activity.
O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy.
A role for O-GlcNAcylation in setting circadian clock speed.
O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation.
Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin.
Altered calcium signaling in colonic smooth muscle of type 1 diabetic mice.
Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle.
Suppressive regulation of KSHV RTA with O-GlcNAcylation.
The transcription factor Sp1 is responsible for aging-dependent altered nucleocytoplasmic trafficking.
Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-β-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes.
Characterization of O-GlcNAcylation in starfish (Asterina pectinifera) development from fertilization to bipinnaria larva.
Protein O-GlcNAcylation regulates Drosophila growth through the insulin signaling pathway.
Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE-/- mice.
Role of the O-linked β-N-acetylglucosamine in the cardioprotection induced by isoflurane.
O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver.
Isoform-specific regulation of the inositol 1,4,5-trisphosphate receptor by O-linked glycosylation.
Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis.
O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans.
Hexosamines stimulate apoptosis by altering SIRT1 action and levels in rodent pancreatic β-cells.
Stress-induced expression of the p75 neurotrophin receptor is regulated by O-GlcNAcylation of the Sp1 transcription factor.
A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome.
O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy.
Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy.
O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18.
OGA inhibition by GlcNAc-selenazoline.
O-GlcNAcylation/phosphorylation cycling at Ser10 controls both transcriptional activity and stability of delta-lactoferrin.
Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure.
Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose.
Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux.
Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes.
Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors.
Mapping of O-linked beta-N-acetylglucosamine modification sites in key contractile proteins of rat skeletal muscle.
Immunochemical methods for the rapid screening of the o-glycosidically linked N-acetylglucosamine modification of proteins.
Posttranslational modifications on protein kinase c isozymes. Effects of epinephrine and phorbol esters.
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes.
Galectin-4 is involved in p27-mediated activation of the myelin basic protein promoter.
Myosin16b: The COOH-tail region directs localization to the nucleus and overexpression delays S-phase progression.
O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes.
Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation.
Stabilization of plakoglobin and enhanced keratinocyte cell-cell adhesion by intracellular O-glycosylation.
The feeder layer-mediated extended lifetime of cultured human skin keratinocytes is associated with altered levels of the transcription factors Sp1 and Sp3.
Posttranslational, reversible O-glycosylation is stimulated by high glucose and mediates plasminogen activator inhibitor-1 gene expression and Sp1 transcriptional activity in glomerular mesangial cells.
Insulin dynamically regulates calmodulin gene expression by sequential o-glycosylation and phosphorylation of sp1 and its subcellular compartmentalization in liver cells.
Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.
Nuclear localization of STAT5A modified with O-linked N-acetylglucosamine and early involution in the mammary gland of Hirosaki hairless rat.
The tumor suppressor HIC1 (hypermethylated in cancer 1) is O-GlcNAc glycosylated.
Regulation of a COPII component by cytosolic O-glycosylation during mitosis.
Identification of O-linked N-acetylglucosamine proteins in rat skeletal muscle using two-dimensional gel electrophoresis and mass spectrometry.
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.
Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1.
Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1.
Elevated expression of O-GlcNAc-modified proteins and O-GlcNAc transferase in corneas of diabetic Goto-Kakizaki rats.
High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.
26S proteasome subunits are O-linked N-acetylglucosamine-modified in Drosophila melanogaster.
Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cells.
Down-regulation of Sp1 activity through modulation of O-glycosylation by treatment with a low glucose mimetic, 2-deoxyglucose.
Immunological detection of O-GlcNAc.
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells.
Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms.
Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles.
Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation.
Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosis.
The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase.
Modulation of CCAAT/enhancer-binding protein-alpha gene expression by metabolic signals in rodent adipocytes.
Interaction of the transcription factor Sp1 with the nuclear pore protein p62 requires the C-terminal domain of p62.
Interaction of the transcription factor Sp1 with the nuclear pore protein p62 requires the C-terminal domain of p62.
O-linked glycoproteins of the nuclear pore complex interact with a cytosolic factor required for nuclear protein import.
Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.
Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.
Nagy T, Kátai E, Fisi V, Takács TT, Stréda A, Wittmann I, Miseta A
Frontiers in immunology 2018;9:970
Frontiers in immunology 2018;9:970
Changes in Protein O-GlcNAcylation During Mouse Epididymal Sperm Maturation.
Tourzani DA, Paudel B, Miranda PV, Visconti PE, Gervasi MG
Frontiers in cell and developmental biology 2018;6:60
Frontiers in cell and developmental biology 2018;6:60
Synaptic protein changes after a chronic period of sensorimotor perturbation in adult rats: a potential role of phosphorylation/O-GlcNAcylation interplay.
Fourneau J, Canu MH, Cieniewski-Bernard C, Bastide B, Dupont E
Journal of neurochemistry 2018 Oct;147(2):240-255
Journal of neurochemistry 2018 Oct;147(2):240-255
O-Linked N-Acetylglucosamine Transiently Elevates in HeLa Cells during Mitosis.
Fisi V, Kátai E, Orbán J, Dossena S, Miseta A, Nagy T
Molecules (Basel, Switzerland) 2018 May 26;23(6)
Molecules (Basel, Switzerland) 2018 May 26;23(6)
Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice.
Ida S, Morino K, Sekine O, Ohashi N, Kume S, Chano T, Iwasaki K, Harada N, Inagaki N, Ugi S, Maegawa H
Diabetologia 2017 Sep;60(9):1761-1769
Diabetologia 2017 Sep;60(9):1761-1769
Mitochondrial O-GlcNAc Transferase (mOGT) Regulates Mitochondrial Structure, Function, and Survival in HeLa Cells.
Sacoman JL, Dagda RY, Burnham-Marusich AR, Dagda RK, Berninsone PM
The Journal of biological chemistry 2017 Mar 17;292(11):4499-4518
The Journal of biological chemistry 2017 Mar 17;292(11):4499-4518
LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice.
Fan Q, Nørgaard RC, Bindesbøll C, Lucas C, Dalen KT, Babaie E, Itkonen HM, Matthews J, Nebb HI, Grønning-Wang LM
Nutrients 2017 Jun 29;9(7)
Nutrients 2017 Jun 29;9(7)
A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis.
Park SK, Zhou X, Pendleton KE, Hunter OV, Kohler JJ, O'Donnell KA, Conrad NK
Cell reports 2017 Aug 1;20(5):1088-1099
Cell reports 2017 Aug 1;20(5):1088-1099
Exercise training increases protein O-GlcNAcylation in rat skeletal muscle.
Hortemo KH, Lunde PK, Anonsen JH, Kvaløy H, Munkvik M, Rehn TA, Sjaastad I, Lunde IG, Aronsen JM, Sejersted OM
Physiological reports 2016 Sep;4(18)
Physiological reports 2016 Sep;4(18)
O-GlcNAcylation is a key modulator of skeletal muscle sarcomeric morphometry associated to modulation of protein-protein interactions.
Lambert M, Richard E, Duban-Deweer S, Krzewinski F, Deracinois B, Dupont E, Bastide B, Cieniewski-Bernard C
Biochimica et biophysica acta 2016 Sep;1860(9):2017-30
Biochimica et biophysica acta 2016 Sep;1860(9):2017-30
Downregulation of O-linked N-acetylglucosamine transferase by RNA interference decreases MMP9 expression in human esophageal cancer cells.
Qiao Z, Dang C, Zhou B, Li S, Zhang W, Jiang J, Zhang J, Ma Y, Kong R, Ma Z
Oncology letters 2016 May;11(5):3317-3323
Oncology letters 2016 May;11(5):3317-3323
Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation.
Akan I, Love DC, Harwood KR, Bond MR, Hanover JA
The Journal of biological chemistry 2016 May 6;291(19):9906-19
The Journal of biological chemistry 2016 May 6;291(19):9906-19
Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer's disease.
Gatta E, Lefebvre T, Gaetani S, dos Santos M, Marrocco J, Mir AM, Cassano T, Maccari S, Nicoletti F, Mairesse J
Pharmacological research 2016 Mar;105:186-97
Pharmacological research 2016 Mar;105:186-97
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells.
Myers SA, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, Thomas S, Maynard J, Broeker M, Thomson M, Pollard K, Yamanaka S, Burlingame AL, Panning B
eLife 2016 Mar 7;5:e10647
eLife 2016 Mar 7;5:e10647
4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition.
Ishizuka S, Askew EB, Ishizuka N, Knudson CB, Knudson W
The Journal of biological chemistry 2016 Jun 3;291(23):12087-104
The Journal of biological chemistry 2016 Jun 3;291(23):12087-104
Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18.
Kakade PS, Budnar S, Kalraiya RD, Vaidya MM
The Journal of biological chemistry 2016 Jun 3;291(23):12003-13
The Journal of biological chemistry 2016 Jun 3;291(23):12003-13
O-GlcNAcylation enhances anaplastic thyroid carcinoma malignancy.
Cheng YU, Li H, Li J, Li J, Gao Y, Liu B
Oncology letters 2016 Jul;12(1):572-578
Oncology letters 2016 Jul;12(1):572-578
Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration.
Wang AC, Jensen EH, Rexach JE, Vinters HV, Hsieh-Wilson LC
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 27;113(52):15120-15125
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 27;113(52):15120-15125
O-GlcNAc cycling enzymes control vascular development of the placenta by modulating the levels of HIF-1α.
Yang YR, Jang HJ, Lee YH, Kim IS, Lee H, Ryu SH, Suh PG
Placenta 2015 Oct;36(10):1063-8
Placenta 2015 Oct;36(10):1063-8
Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling.
Yang YR, Kim DH, Seo YK, Park D, Jang HJ, Choi SY, Lee YH, Lee GH, Nakajima K, Taniguchi N, Kim JM, Choi EJ, Moon HY, Kim IS, Choi JH, Lee H, Ryu SH, Cocco L, Suh PG
Oncotarget 2015 May 20;6(14):12529-42
Oncotarget 2015 May 20;6(14):12529-42
Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis.
Keembiyehetty C, Love DC, Harwood KR, Gavrilova O, Comly ME, Hanover JA
The Journal of biological chemistry 2015 Mar 13;290(11):7097-113
The Journal of biological chemistry 2015 Mar 13;290(11):7097-113
Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle.
Hortemo KH, Aronsen JM, Lunde IG, Sjaastad I, Lunde PK, Sejersted OM
Physiological reports 2015 Feb 1;3(2)
Physiological reports 2015 Feb 1;3(2)
O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster.
Park S, Lee Y, Pak JW, Kim H, Choi H, Kim JW, Roth J, Cho JW
Cellular and molecular life sciences : CMLS 2015 Aug;72(16):3173-83
Cellular and molecular life sciences : CMLS 2015 Aug;72(16):3173-83
Conserved nutrient sensor O-GlcNAc transferase is integral to C. elegans pathogen-specific immunity.
Bond MR, Ghosh SK, Wang P, Hanover JA
PloS one 2014;9(12):e113231
PloS one 2014;9(12):e113231
X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body.
Olivier-Van Stichelen S, Hanover JA
Frontiers in genetics 2014;5:256
Frontiers in genetics 2014;5:256
Inhibition of mTOR affects protein stability of OGT.
Park S, Pak J, Jang I, Cho JW
Biochemical and biophysical research communications 2014 Oct 17;453(2):208-12
Biochemical and biophysical research communications 2014 Oct 17;453(2):208-12
Phospho-GlcNAc modulation of slow MLC2 during soleus atrophy through a multienzymatic and sarcomeric complex.
Cieniewski-Bernard C, Dupont E, Richard E, Bastide B
Pflugers Archiv : European journal of physiology 2014 Nov;466(11):2139-51
Pflugers Archiv : European journal of physiology 2014 Nov;466(11):2139-51
OGA heterozygosity suppresses intestinal tumorigenesis in Apc(min/+) mice.
Yang YR, Jang HJ, Yoon S, Lee YH, Nam D, Kim IS, Lee H, Kim H, Choi JH, Kang BH, Ryu SH, Suh PG
Oncogenesis 2014 Jul 7;3:e109
Oncogenesis 2014 Jul 7;3:e109
Oral glucosamine sulfate supplementation does not induce endoplasmic reticulum stress or activate the unfolded protein response in circulating leukocytes of human subjects.
McAlpine CS, Beriault DR, Behdinan T, Shi Y, Werstuck GH
Canadian journal of physiology and pharmacology 2014 Apr;92(4):285-91
Canadian journal of physiology and pharmacology 2014 Apr;92(4):285-91
Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy.
Graham DL, Gray AJ, Joyce JA, Yu D, O'Moore J, Carlson GA, Shearman MS, Dellovade TL, Hering H
Neuropharmacology 2014 Apr;79:307-13
Neuropharmacology 2014 Apr;79:307-13
Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers.
Kizuka Y, Kitazume S, Okahara K, Villagra A, Sotomayor EM, Taniguchi N
The Journal of biological chemistry 2014 Apr 18;289(16):11253-61
The Journal of biological chemistry 2014 Apr 18;289(16):11253-61
Hexosamine biosynthesis is a possible mechanism underlying hypoxia's effects on lipid metabolism in human adipocytes.
O'Rourke RW, Meyer KA, Gaston G, White AE, Lumeng CN, Marks DL
PloS one 2013;8(8):e71165
PloS one 2013;8(8):e71165
Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.
Borghgraef P, Menuet C, Theunis C, Louis JV, Devijver H, Maurin H, Smet-Nocca C, Lippens G, Hilaire G, Gijsen H, Moechars D, Van Leuven F
PloS one 2013;8(12):e84442
PloS one 2013;8(12):e84442
A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2.
Palaniappan KK, Hangauer MJ, Smith TJ, Smart BP, Pitcher AA, Cheng EH, Bertozzi CR, Boyce M
Cell reports 2013 Oct 31;5(2):546-52
Cell reports 2013 Oct 31;5(2):546-52
Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400.
Cameron A, Giacomozzi B, Joyce J, Gray A, Graham D, Ousson S, Neny M, Beher D, Carlson G, O'Moore J, Shearman M, Hering H
FEBS letters 2013 Nov 15;587(22):3722-8
FEBS letters 2013 Nov 15;587(22):3722-8
CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease.
Jin N, Qian W, Yin X, Zhang L, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F
Nucleic acids research 2013 Mar 1;41(5):3240-56
Nucleic acids research 2013 Mar 1;41(5):3240-56
Potential regulation of human muscle plasticity by MLC2 post-translational modifications during bed rest and countermeasures.
Stevens L, Bastide B, Hedou J, Cieniewski-Bernard C, Montel V, Cochon L, Dupont E, Mounier Y
Archives of biochemistry and biophysics 2013 Dec;540(1-2):125-32
Archives of biochemistry and biophysics 2013 Dec;540(1-2):125-32
Requirement of decreased O-GlcNAc glycosylation of Mef2D for its recruitment to the myogenin promoter.
Ogawa M, Sakakibara Y, Kamemura K
Biochemical and biophysical research communications 2013 Apr 19;433(4):558-62
Biochemical and biophysical research communications 2013 Apr 19;433(4):558-62
The increase in O-linked N-acetylglucosamine protein modification stimulates chondrogenic differentiation both in vitro and in vivo.
Andrés-Bergós J, Tardio L, Larranaga-Vera A, Gómez R, Herrero-Beaumont G, Largo R
The Journal of biological chemistry 2012 Sep 28;287(40):33615-28
The Journal of biological chemistry 2012 Sep 28;287(40):33615-28
Rescue of the transcription factors Sp1 and NFI in human skin keratinocytes through a feeder-layer-dependent suppression of the proteasome activity.
Duval C, Gaudreault M, Vigneault F, Touzel-Deschênes L, Rochette PJ, Masson-Gadais B, Germain L, Guérin SL
Journal of molecular biology 2012 May 18;418(5):281-99
Journal of molecular biology 2012 May 18;418(5):281-99
O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy.
Facundo HT, Brainard RE, Watson LJ, Ngoh GA, Hamid T, Prabhu SD, Jones SP
American journal of physiology. Heart and circulatory physiology 2012 May 15;302(10):H2122-30
American journal of physiology. Heart and circulatory physiology 2012 May 15;302(10):H2122-30
A role for O-GlcNAcylation in setting circadian clock speed.
Kim EY, Jeong EH, Park S, Jeong HJ, Edery I, Cho JW
Genes & development 2012 Mar 1;26(5):490-502
Genes & development 2012 Mar 1;26(5):490-502
O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation.
Zhu Q, Zhou L, Yang Z, Lai M, Xie H, Wu L, Xing C, Zhang F, Zheng S
Medical oncology (Northwood, London, England) 2012 Jun;29(2):985-93
Medical oncology (Northwood, London, England) 2012 Jun;29(2):985-93
Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin.
Ise H, Goto M, Komura K, Akaike T
Glycobiology 2012 Jun;22(6):788-805
Glycobiology 2012 Jun;22(6):788-805
Altered calcium signaling in colonic smooth muscle of type 1 diabetic mice.
Touw K, Chakraborty S, Zhang W, Obukhov AG, Tune JD, Gunst SJ, Herring BP
American journal of physiology. Gastrointestinal and liver physiology 2012 Jan 1;302(1):G66-76
American journal of physiology. Gastrointestinal and liver physiology 2012 Jan 1;302(1):G66-76
Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle.
Habegger KM, Penque BA, Sealls W, Tackett L, Bell LN, Blue EK, Gallagher PJ, Sturek M, Alloosh MA, Steinberg HO, Considine RV, Elmendorf JS
Diabetologia 2012 Feb;55(2):457-67
Diabetologia 2012 Feb;55(2):457-67
Suppressive regulation of KSHV RTA with O-GlcNAcylation.
Ko YC, Tsai WH, Wang PW, Wu IL, Lin SY, Chen YL, Chen JY, Lin SF
Journal of biomedical science 2012 Feb 2;19:12
Journal of biomedical science 2012 Feb 2;19:12
The transcription factor Sp1 is responsible for aging-dependent altered nucleocytoplasmic trafficking.
Kim SY, Kang HT, Han JA, Park SC
Aging cell 2012 Dec;11(6):1102-9
Aging cell 2012 Dec;11(6):1102-9
Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-β-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes.
Gawlowski T, Suarez J, Scott B, Torres-Gonzalez M, Wang H, Schwappacher R, Han X, Yates JR 3rd, Hoshijima M, Dillmann W
The Journal of biological chemistry 2012 Aug 24;287(35):30024-34
The Journal of biological chemistry 2012 Aug 24;287(35):30024-34
Characterization of O-GlcNAcylation in starfish (Asterina pectinifera) development from fertilization to bipinnaria larva.
Ogawa M, Adachi T, Ikegami S, Kato KH, Yamamoto A, Kamemura K
Bioscience, biotechnology, and biochemistry 2011;75(2):358-61
Bioscience, biotechnology, and biochemistry 2011;75(2):358-61
Protein O-GlcNAcylation regulates Drosophila growth through the insulin signaling pathway.
Park S, Park SH, Baek JY, Jy YJ, Kim KS, Roth J, Cho JW, Choe KM
Cellular and molecular life sciences : CMLS 2011 Oct;68(20):3377-84
Cellular and molecular life sciences : CMLS 2011 Oct;68(20):3377-84
Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE-/- mice.
Beriault DR, Sharma S, Shi Y, Khan MI, Werstuck GH
Atherosclerosis 2011 Nov;219(1):134-40
Atherosclerosis 2011 Nov;219(1):134-40
Role of the O-linked β-N-acetylglucosamine in the cardioprotection induced by isoflurane.
Hirose K, Tsutsumi YM, Tsutsumi R, Shono M, Katayama E, Kinoshita M, Tanaka K, Oshita S
Anesthesiology 2011 Nov;115(5):955-62
Anesthesiology 2011 Nov;115(5):955-62
O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver.
Guinez C, Filhoulaud G, Rayah-Benhamed F, Marmier S, Dubuquoy C, Dentin R, Moldes M, Burnol AF, Yang X, Lefebvre T, Girard J, Postic C
Diabetes 2011 May;60(5):1399-413
Diabetes 2011 May;60(5):1399-413
Isoform-specific regulation of the inositol 1,4,5-trisphosphate receptor by O-linked glycosylation.
Bimboese P, Gibson CJ, Schmidt S, Xiang W, Ehrlich BE
The Journal of biological chemistry 2011 May 6;286(18):15688-97
The Journal of biological chemistry 2011 May 6;286(18):15688-97
Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis.
Shin SH, Love DC, Hanover JA
Amino acids 2011 Mar;40(3):885-93
Amino acids 2011 Mar;40(3):885-93
O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans.
Mondoux MA, Love DC, Ghosh SK, Fukushige T, Bond M, Weerasinghe GR, Hanover JA, Krause MW
Genetics 2011 Jun;188(2):369-82
Genetics 2011 Jun;188(2):369-82
Hexosamines stimulate apoptosis by altering SIRT1 action and levels in rodent pancreatic β-cells.
Lafontaine-Lacasse M, Doré G, Picard F
The Journal of endocrinology 2011 Jan;208(1):41-9
The Journal of endocrinology 2011 Jan;208(1):41-9
Stress-induced expression of the p75 neurotrophin receptor is regulated by O-GlcNAcylation of the Sp1 transcription factor.
Kommaddi RP, Dickson KM, Barker PA
Journal of neurochemistry 2011 Feb;116(3):396-405
Journal of neurochemistry 2011 Feb;116(3):396-405
A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome.
Keembiyehetty CN, Krzeslak A, Love DC, Hanover JA
Journal of cell science 2011 Aug 15;124(Pt 16):2851-60
Journal of cell science 2011 Aug 15;124(Pt 16):2851-60
O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy.
Mi W, Gu Y, Han C, Liu H, Fan Q, Zhang X, Cong Q, Yu W
Biochimica et biophysica acta 2011 Apr;1812(4):514-9
Biochimica et biophysica acta 2011 Apr;1812(4):514-9
Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy.
Yokoe S, Asahi M, Takeda T, Otsu K, Taniguchi N, Miyoshi E, Suzuki K
Glycobiology 2010 Oct;20(10):1217-26
Glycobiology 2010 Oct;20(10):1217-26
O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18.
Srikanth B, Vaidya MM, Kalraiya RD
The Journal of biological chemistry 2010 Oct 29;285(44):34062-71
The Journal of biological chemistry 2010 Oct 29;285(44):34062-71
OGA inhibition by GlcNAc-selenazoline.
Kim EJ, Love DC, Darout E, Abdo M, Rempel B, Withers SG, Rablen PR, Hanover JA, Knapp S
Bioorganic & medicinal chemistry 2010 Oct 1;18(19):7058-64
Bioorganic & medicinal chemistry 2010 Oct 1;18(19):7058-64
O-GlcNAcylation/phosphorylation cycling at Ser10 controls both transcriptional activity and stability of delta-lactoferrin.
Hardivillé S, Hoedt E, Mariller C, Benaïssa M, Pierce A
The Journal of biological chemistry 2010 Jun 18;285(25):19205-18
The Journal of biological chemistry 2010 Jun 18;285(25):19205-18
Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure.
D'Apolito M, Du X, Zong H, Catucci A, Maiuri L, Trivisano T, Pettoello-Mantovani M, Campanozzi A, Raia V, Pessin JE, Brownlee M, Giardino I
The Journal of clinical investigation 2010 Jan;120(1):203-13
The Journal of clinical investigation 2010 Jan;120(1):203-13
Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose.
Anthonisen EH, Berven L, Holm S, Nygård M, Nebb HI, Grønning-Wang LM
The Journal of biological chemistry 2010 Jan 15;285(3):1607-15
The Journal of biological chemistry 2010 Jan 15;285(3):1607-15
Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux.
James LR, Le C, Scholey JW
American journal of physiology. Endocrinology and metabolism 2010 Feb;298(2):E210-21
American journal of physiology. Endocrinology and metabolism 2010 Feb;298(2):E210-21
Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes.
Whelan SA, Dias WB, Thiruneelakantapillai L, Lane MD, Hart GW
The Journal of biological chemistry 2010 Feb 19;285(8):5204-11
The Journal of biological chemistry 2010 Feb 19;285(8):5204-11
Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors.
Kodiha M, Tran D, Morogan A, Qian C, Stochaj U
PloS one 2009 Dec 24;4(12):e8420
PloS one 2009 Dec 24;4(12):e8420
Mapping of O-linked beta-N-acetylglucosamine modification sites in key contractile proteins of rat skeletal muscle.
Hédou J, Bastide B, Page A, Michalski JC, Morelle W
Proteomics 2009 Apr;9(8):2139-48
Proteomics 2009 Apr;9(8):2139-48
Immunochemical methods for the rapid screening of the o-glycosidically linked N-acetylglucosamine modification of proteins.
Ahrend M, Käberich A, Fergen MT, Schmitz B
Methods in molecular biology (Clifton, N.J.) 2008;446:267-80
Methods in molecular biology (Clifton, N.J.) 2008;446:267-80
Posttranslational modifications on protein kinase c isozymes. Effects of epinephrine and phorbol esters.
Robles-Flores M, Meléndez L, García W, Mendoza-Hernández G, Lam TT, Castañeda-Patlán C, González-Aguilar H
Biochimica et biophysica acta 2008 May;1783(5):695-712
Biochimica et biophysica acta 2008 May;1783(5):695-712
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
Yao D, Taguchi T, Matsumura T, Pestell R, Edelstein D, Giardino I, Suske G, Rabbani N, Thornalley PJ, Sarthy VP, Hammes HP, Brownlee M
The Journal of biological chemistry 2007 Oct 19;282(42):31038-45
The Journal of biological chemistry 2007 Oct 19;282(42):31038-45
Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes.
Robinson KA, Ball LE, Buse MG
American journal of physiology. Endocrinology and metabolism 2007 Mar;292(3):E884-90
American journal of physiology. Endocrinology and metabolism 2007 Mar;292(3):E884-90
Galectin-4 is involved in p27-mediated activation of the myelin basic protein promoter.
Wei Q, Eviatar-Ribak T, Miskimins WK, Miskimins R
Journal of neurochemistry 2007 Jun;101(5):1214-23
Journal of neurochemistry 2007 Jun;101(5):1214-23
Myosin16b: The COOH-tail region directs localization to the nucleus and overexpression delays S-phase progression.
Cameron RS, Liu C, Mixon AS, Pihkala JP, Rahn RJ, Cameron PL
Cell motility and the cytoskeleton 2007 Jan;64(1):19-48
Cell motility and the cytoskeleton 2007 Jan;64(1):19-48
O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes.
Dehennaut V, Lefebvre T, Sellier C, Leroy Y, Gross B, Walker S, Cacan R, Michalski JC, Vilain JP, Bodart JF
The Journal of biological chemistry 2007 Apr 27;282(17):12527-36
The Journal of biological chemistry 2007 Apr 27;282(17):12527-36
Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation.
Martín A, Rojas S, Chamorro A, Falcón C, Bargalló N, Planas AM
Stroke 2006 May;37(5):1288-95
Stroke 2006 May;37(5):1288-95
Stabilization of plakoglobin and enhanced keratinocyte cell-cell adhesion by intracellular O-glycosylation.
Hu P, Berkowitz P, Madden VJ, Rubenstein DS
The Journal of biological chemistry 2006 May 5;281(18):12786-91
The Journal of biological chemistry 2006 May 5;281(18):12786-91
The feeder layer-mediated extended lifetime of cultured human skin keratinocytes is associated with altered levels of the transcription factors Sp1 and Sp3.
Masson-Gadais B, Fugère C, Paquet C, Leclerc S, Lefort NR, Germain L, Guérin SL
Journal of cellular physiology 2006 Mar;206(3):831-42
Journal of cellular physiology 2006 Mar;206(3):831-42
Posttranslational, reversible O-glycosylation is stimulated by high glucose and mediates plasminogen activator inhibitor-1 gene expression and Sp1 transcriptional activity in glomerular mesangial cells.
Goldberg HJ, Whiteside CI, Hart GW, Fantus IG
Endocrinology 2006 Jan;147(1):222-31
Endocrinology 2006 Jan;147(1):222-31
Insulin dynamically regulates calmodulin gene expression by sequential o-glycosylation and phosphorylation of sp1 and its subcellular compartmentalization in liver cells.
Majumdar G, Harrington A, Hungerford J, Martinez-Hernandez A, Gerling IC, Raghow R, Solomon S
The Journal of biological chemistry 2006 Feb 10;281(6):3642-50
The Journal of biological chemistry 2006 Feb 10;281(6):3642-50
Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.
Forsythe ME, Love DC, Lazarus BD, Kim EJ, Prinz WA, Ashwell G, Krause MW, Hanover JA
Proceedings of the National Academy of Sciences of the United States of America 2006 Aug 8;103(32):11952-7
Proceedings of the National Academy of Sciences of the United States of America 2006 Aug 8;103(32):11952-7
Nuclear localization of STAT5A modified with O-linked N-acetylglucosamine and early involution in the mammary gland of Hirosaki hairless rat.
Nanashima N, Asano J, Hayakari M, Nakamura T, Nakano H, Yamada T, Shimizu T, Akita M, Fan Y, Tsuchida S
The Journal of biological chemistry 2005 Dec 30;280(52):43010-6
The Journal of biological chemistry 2005 Dec 30;280(52):43010-6
The tumor suppressor HIC1 (hypermethylated in cancer 1) is O-GlcNAc glycosylated.
Lefebvre T, Pinte S, Guérardel C, Deltour S, Martin-Soudant N, Slomianny MC, Michalski JC, Leprince D
European journal of biochemistry 2004 Oct;271(19):3843-54
European journal of biochemistry 2004 Oct;271(19):3843-54
Regulation of a COPII component by cytosolic O-glycosylation during mitosis.
Dudognon P, Maeder-Garavaglia C, Carpentier JL, Paccaud JP
FEBS letters 2004 Mar 12;561(1-3):44-50
FEBS letters 2004 Mar 12;561(1-3):44-50
Identification of O-linked N-acetylglucosamine proteins in rat skeletal muscle using two-dimensional gel electrophoresis and mass spectrometry.
Cieniewski-Bernard C, Bastide B, Lefebvre T, Lemoine J, Mounier Y, Michalski JC
Molecular & cellular proteomics : MCP 2004 Jun;3(6):577-85
Molecular & cellular proteomics : MCP 2004 Jun;3(6):577-85
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G
Endocrinology 2004 Jun;145(6):2845-57
Endocrinology 2004 Jun;145(6):2845-57
O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.
Liu F, Iqbal K, Grundke-Iqbal I, Hart GW, Gong CX
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 20;101(29):10804-9
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 20;101(29):10804-9
Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1.
Majumdar G, Wright J, Markowitz P, Martinez-Hernandez A, Raghow R, Solomon SS
Diabetes 2004 Dec;53(12):3184-92
Diabetes 2004 Dec;53(12):3184-92
Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1.
Majumdar G, Wright J, Markowitz P, Martinez-Hernandez A, Raghow R, Solomon SS
Diabetes 2004 Dec;53(12):3184-92
Diabetes 2004 Dec;53(12):3184-92
Elevated expression of O-GlcNAc-modified proteins and O-GlcNAc transferase in corneas of diabetic Goto-Kakizaki rats.
Akimoto Y, Kawakami H, Yamamoto K, Munetomo E, Hida T, Hirano H
Investigative ophthalmology & visual science 2003 Sep;44(9):3802-9
Investigative ophthalmology & visual science 2003 Sep;44(9):3802-9
High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.
Walgren JL, Vincent TS, Schey KL, Buse MG
American journal of physiology. Endocrinology and metabolism 2003 Feb;284(2):E424-34
American journal of physiology. Endocrinology and metabolism 2003 Feb;284(2):E424-34
26S proteasome subunits are O-linked N-acetylglucosamine-modified in Drosophila melanogaster.
Sümegi M, Hunyadi-Gulyás E, Medzihradszky KF, Udvardy A
Biochemical and biophysical research communications 2003 Dec 26;312(4):1284-9
Biochemical and biophysical research communications 2003 Dec 26;312(4):1284-9
Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cells.
Brasse-Lagnel C, Fairand A, Lavoinne A, Husson A
The Journal of biological chemistry 2003 Dec 26;278(52):52504-10
The Journal of biological chemistry 2003 Dec 26;278(52):52504-10
Down-regulation of Sp1 activity through modulation of O-glycosylation by treatment with a low glucose mimetic, 2-deoxyglucose.
Kang HT, Ju JW, Cho JW, Hwang ES
The Journal of biological chemistry 2003 Dec 19;278(51):51223-31
The Journal of biological chemistry 2003 Dec 19;278(51):51223-31
Immunological detection of O-GlcNAc.
Rex-Mathes M, Koch J, Werner S, Griffith LS, Schmitz B
Methods in molecular biology (Clifton, N.J.) 2002;194:73-87
Methods in molecular biology (Clifton, N.J.) 2002;194:73-87
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells.
Federici M, Menghini R, Mauriello A, Hribal ML, Ferrelli F, Lauro D, Sbraccia P, Spagnoli LG, Sesti G, Lauro R
Circulation 2002 Jul 23;106(4):466-72
Circulation 2002 Jul 23;106(4):466-72
Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms.
Zhang P, Klenk ES, Lazzaro MA, Williams LB, Considine RV
Endocrinology 2002 Jan;143(1):99-106
Endocrinology 2002 Jan;143(1):99-106
Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles.
Buse MG, Robinson KA, Marshall BA, Hresko RC, Mueckler MM
American journal of physiology. Endocrinology and metabolism 2002 Aug;283(2):E241-50
American journal of physiology. Endocrinology and metabolism 2002 Aug;283(2):E241-50
Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation.
James LR, Tang D, Ingram A, Ly H, Thai K, Cai L, Scholey JW
Diabetes 2002 Apr;51(4):1146-56
Diabetes 2002 Apr;51(4):1146-56
Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosis.
Zhu W, Leber B, Andrews DW
The EMBO journal 2001 Nov 1;20(21):5999-6007
The EMBO journal 2001 Nov 1;20(21):5999-6007
The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase.
Konrad RJ, Mikolaenko I, Tolar JF, Liu K, Kudlow JE
The Biochemical journal 2001 May 15;356(Pt 1):31-41
The Biochemical journal 2001 May 15;356(Pt 1):31-41
Modulation of CCAAT/enhancer-binding protein-alpha gene expression by metabolic signals in rodent adipocytes.
Wang Y, Lee-Kwon W, Martindale JL, Adams L, Heller P, Egan JM, Bernier M
Endocrinology 1999 Jul;140(7):2938-47
Endocrinology 1999 Jul;140(7):2938-47
Interaction of the transcription factor Sp1 with the nuclear pore protein p62 requires the C-terminal domain of p62.
Han I, Roos MD, Kudlow JE
Journal of cellular biochemistry 1998 Jan 1;68(1):50-61
Journal of cellular biochemistry 1998 Jan 1;68(1):50-61
Interaction of the transcription factor Sp1 with the nuclear pore protein p62 requires the C-terminal domain of p62.
Han I, Roos MD, Kudlow JE
Journal of cellular biochemistry 1998 Jan 1;68(1):50-61
Journal of cellular biochemistry 1998 Jan 1;68(1):50-61
O-linked glycoproteins of the nuclear pore complex interact with a cytosolic factor required for nuclear protein import.
Sterne-Marr R, Blevitt JM, Gerace L
The Journal of cell biology 1992 Jan;116(2):271-80
The Journal of cell biology 1992 Jan;116(2):271-80
Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.
Holt GD, Snow CM, Senior A, Haltiwanger RS, Gerace L, Hart GW
The Journal of cell biology 1987 May;104(5):1157-64
The Journal of cell biology 1987 May;104(5):1157-64
Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.
Snow CM, Senior A, Gerace L
The Journal of cell biology 1987 May;104(5):1143-56
The Journal of cell biology 1987 May;104(5):1143-56
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- Main image
- Experimental details
- Western blot analysis of mouse cortical brain lysates using O-Linked N-Acetylglucosamine Monoclonal Antibody (Product # MA1-072). Blots containing cortical extracts from 4 individual C57BL/6 mice (Lanes 1-4) were blocked with 5% milk in TBST, and probed with MA1-072 (1:1000), followed by a fluorophore-conjugated goat anti-mouse IgG secondary antibody. Data courtesy of the Innovators Program.
