Explore
Validate
LearnABIN1881196
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN1881196 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) (N-Term), (AA 111-141) antibody
- Antibody type
- Polyclonal
- Antigen
- This CHEK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-141 amino acids from the N-terminal region of human CHEK2.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term,AA 111-141
- Antibody clone number
- RB19067
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.
A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells.
Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
Yang X, Wood PA, Hrushesky WJ
The Journal of biological chemistry 2010 Jan 29;285(5):3030-4
The Journal of biological chemistry 2010 Jan 29;285(5):3030-4
A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells.
Varmark H, Kwak S, Theurkauf WE
Cell cycle (Georgetown, Tex.) 2010 Jan 15;9(2):312-20
Cell cycle (Georgetown, Tex.) 2010 Jan 15;9(2):312-20
Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
Zhu H, Miao ZH, Huang M, Feng JM, Zhang ZX, Lu JJ, Cai YJ, Tong LJ, Xu YF, Qian XH, Ding J
Neoplasia (New York, N.Y.) 2009 Nov;11(11):1226-34
Neoplasia (New York, N.Y.) 2009 Nov;11(11):1226-34
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- CHEK2 Antibody (N-term) (ABIN1881196) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- CHEK2 Antibody (N-term) (ABIN1881196) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- CHEK2 Antibody (N-term) (ABIN1881196) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- CHEK2 Antibody (N-term) (ABIN1881196) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
