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LearnPAB16966
antibody from Abnova Corporation
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB16966 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB16966, RRID:AB_10615897
- Product name
- CHEK2 (phospho T387) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of CHEK2.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Autophosphorylated residues involved in the regulation of human chk2 in vitro.
Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2.
The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
Gabant G, Lorphelin A, Nozerand N, Marchetti C, Bellanger L, Dedieu A, Quéméneur E, Alpha-Bazin B
Journal of molecular biology 2008 Jul 11;380(3):489-503
Journal of molecular biology 2008 Jul 11;380(3):489-503
Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2.
Gupta SK, Guo X, Durkin SS, Fryrear KF, Ward MD, Semmes OJ
The Journal of biological chemistry 2007 Oct 5;282(40):29431-40
The Journal of biological chemistry 2007 Oct 5;282(40):29431-40
The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
Oliva-Trastoy M, Berthonaud V, Chevalier A, Ducrot C, Marsolier-Kergoat MC, Mann C, Leteurtre F
Oncogene 2007 Mar 1;26(10):1449-58
Oncogene 2007 Mar 1;26(10):1449-58
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot of Jurkat cells using CHEK2 (phospho Thr387) polyclonal antibody (Cat # PAB16966).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma tissue using CHEK2 (phospho Thr387) polyclonal antibody (Cat # PAB16966).
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
