Tissue expression
Cell line expression
Protein structure
TRIM2
Tripartite motif containing 2CMT2R, KIAA0517, RNF86
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Top validated antibodies |
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Novus Biologicals | NB100-1218 | 2 references | Polyclonal |
WB
EL
IP
IHC
FC
|
|
Proteintech Group | 20356-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 20356-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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antibodies-online | ABIN249847 | 2 references | Polyclonal |
WB
EL
IP
IHC |
|
Everest Biotech | EB05914 | Polyclonal |
WB
EL
IHC
FC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider