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Protein structure
RASGRP2
RAS guanyl releasing protein 2CALDAG-GEFI
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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| antibodies-online |  ABIN954463 |
4 references | Polyclonal |
WB
EL
ICC
IHC
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| Acris Antibodies GmbH | AP53590PU-N |
5 references | Polyclonal |
WB
ICC
IHC
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| GeneTex | GTX108616 |
2 references | Polyclonal |
WB
IP
IHC
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| Invitrogen Antibodies | PA5-28865 |
1 references | Polyclonal |
WB
IHC
OA
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| NovoPro Bioscience Inc. | 118744 |
Polyclonal |
WB
EL
ICC
IHC
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