Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19050-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19050-1-AP, RRID:AB_2188417
- Product name
- SGMS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SGMS1 antibody (Cat. #19050-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Symbiotic Relationship between the Neural Retina and Retinal Pigment Epithelium Is Supported by Utilizing Differential Metabolic Pathways.
Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Dysregulated sphingolipid metabolism in endometriosis.
Sinha T, Naash MI, Al-Ubaidi MR
iScience 2020 Apr 24;23(4):101004
iScience 2020 Apr 24;23(4):101004
Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.
Lu MH, Ji WL, Xu DE, Yao PP, Zhao XY, Wang ZT, Fang LP, Huang R, Lan LJ, Chen JB, Wang TH, Cheng LH, Xu RX, Liu CF, Puglielli L, Ma QH
Experimental neurology 2019 Jan;311:67-79
Experimental neurology 2019 Jan;311:67-79
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Tang YC, Yuwen H, Wang K, Bruno PM, Bullock K, Deik A, Santaguida S, Trakala M, Pfau SJ, Zhong N, Huang T, Wang L, Clish CB, Hemann MT, Amon A
Cancer research 2017 Oct 1;77(19):5272-5286
Cancer research 2017 Oct 1;77(19):5272-5286
Dysregulated sphingolipid metabolism in endometriosis.
Lee YH, Tan CW, Venkatratnam A, Tan CS, Cui L, Loh SF, Griffith L, Tannenbaum SR, Chan JK
The Journal of clinical endocrinology and metabolism 2014 Oct;99(10):E1913-21
The Journal of clinical endocrinology and metabolism 2014 Oct;99(10):E1913-21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 19050-1-AP(SGMS1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 19050-1-AP(SGMS1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SGMS1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SGMS1. This antibody recognizes human, mouse, rat antigen. The SGMS1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.